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    <title>Nature Network - splicing</title>
    <description>The latest taggings for splicing</description>
    <link>http://network.nature.com/announcements</link>
    <language>en-us</language>
    <ttl>40</ttl>
    <item>
      <title>Splicing for muscular dystrophy: toward Morpholino therapeutics</title>
      <description>
        <![CDATA[Jon Moulton - Morpholino antisense oligos can redirect splicing of pre-mRNA. This strategy is being used in development of therapeutic oligos for Duchenne muscular dystrophy. Here are a few references. Papers Vitiello L, Bassi N, Campagnolo P, Zaccariotto E, Occhi G, Malerba A,]]>
      </description>
    </item>
    <item>
      <title>Christine Wells</title>
      <description>
        <![CDATA[Christine Wells - ]]>
      </description>
    </item>
    <item>
      <title>Morpholino activity, duration in mouse</title>
      <description>
        <![CDATA[Jon Moulton - "For example, we have observed continued *exon skipping in the dystrophin transcript up to 14 weeks after a single intramuscular injection of a morpholino* antisense molecule with concomitant expression of a modified dystrophin in the treated muscle of the dystrophic]]>
      </description>
    </item>
    <item>
      <title>Complete control</title>
      <description>
        <![CDATA[Richard Grant - One of the things that we are learning in the doing of Science is that, fundamentally, all things _are_ "interconnected":http://www.amazon.co.uk/Dirk-Gentlys-Holistic-Detective-Agency/dp/customer-reviews/0330301624 . Nowhere is this more apparent than in the familiar Central Dogma, the formation of protein from DNA through the]]>
      </description>
    </item>
    <item>
      <title>What Morpholinos are</title>
      <description>
        <![CDATA[Jon Moulton - Morpholinos are antisense molecules which are specific, stable, effective and nontoxic. They generally are comprised of about 25 nucleic acid bases linked by an uncharged synthetic backbone. They bind to complementary sequences of RNA by base pairing to prevent processes]]>
      </description>
    </item>
    <item>
      <title>Daniel Oberg</title>
      <description>
        <![CDATA[Daniel Oberg - ]]>
      </description>
    </item>
    <item>
      <title>Pierre de la Grange</title>
      <description>
        <![CDATA[Pierre de la Grange - ]]>
      </description>
    </item>
    <item>
      <title>Rasmus Wernersson</title>
      <description>
        <![CDATA[Rasmus Wernersson - ]]>
      </description>
    </item>
    <item>
      <title>Gunnar Raetsch</title>
      <description>
        <![CDATA[Gunnar Raetsch - ]]>
      </description>
    </item>
    <item>
      <title>Break the silence</title>
      <description>
        <![CDATA[Jon Moulton - This has been a quiet forum, so I will try to break the ice. A technique for associating a function with a gene is to knock down the expression of the gene and observe the resulting changes in cells or]]>
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