Ute Christine Rogner's profile

What I do

I have joined the Molecular Genetics Group at the Pasteur Institute as a postdoctoral fellow in 1996 after diploma and Ph.D. studies in Germany and Denmark. I have a permanent staff scientist’s position with the CNRS since October 2002 and I am currently heading a small research team.

Affiliations

Current

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Interests

My research interests include studies on mouse models for polygenic and multifactorial diseases, especially type 1 diabetes and neural tube defects. With my collaborators we are studying the genetic, cellular and molecular basis of these disorders.

Projects

Complex diseases: Genetics of type 1 diabetes in the nonobese diabetic mouse
Epigenetic control of neurulation

Publications

  • Vallois D, Grimm C, Avner P, Boitard C, Rogner U. The type 1 diabetes locus Idd6 controls TLR1 expression. Journal of immunology (Baltimore, Md. : 1950) 179 (6) , 3896-903 (2007) PubMed ID:(17785827)

  • Nap1l2 promotes histone acetylation activity during neuronal differentiation. (Epub 25 Jun 2007) PubMed ID:(17591696)

  • Hung M, Avner P, Rogner U. Identification of the transcription factor ARNTL2 as a candidate gene for the type 1 diabetes locus Idd6. Human molecular genetics 15 (18) , 2732-42 (Epub 07 Aug 2006) PubMed ID:(16893914)

  • Rogner U, Avner P. Congenic mice: cutting tools for complex immune disorders. Nature reviews. Immunology 3 (3) , 243-52 PubMed ID:(12658272)

  • Rogner U, Lepault F, Gagnerault M, Vallois D, Morin J, Avner P, Boitard C. The diabetes type 1 locus Idd6 modulates activity of CD4+CD25+ regulatory T-cells. Diabetes 55 (1) , 186-92 PubMed ID:(16380492)

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