Shina Lynn Kamerlin's profile

I'm female

What I do

Postdoc in computational chemistry in the Warshel Group at the University of Southern California. Interested in studying enzyme reaction mechanisms (particularly of phosphatases and kinases), and phosphate ester hydrolysis.

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Publications

  • Kamerlin S, Florián J, Warshel A. Associative Versus Dissociative Mechanisms of Phosphate Monoester Hydrolysis: On the Interpretation of Activation Entropies ChemPhysChem 9 (12) , 1767 - 1773 (2008) doi: 10.1002/cphc.200800356

  • Kamerlin S, Williams N, Warshel A. Dineopentyl Phosphate Hydrolysis: Evidence for Stepwise Water Attack J. Org. Chem. 73 (18) , 6960 - 6969 (2008) doi: 10.1021/jo801207q

  • Rosta E, Kamerlin S, Warshel A. On the Interpretation of the Observed Linear Free Energy Relationship in Phosphate Hydrolysis: A Thorough Computational Study of Phosphate Diester Hydrolysis in Solution Biochemistry 47 (12) , 3725 - 3735 (2008) doi: 10.1021/bi702106m

  • Kamerlin SCL, Wilkie J. The role of metal ions in phosphate ester hydrolysis. Recent Advances in Inorganic Pyrophosphatase Research , 21829 (2004)

  • KAMERLIN S, RUCKER R, BORESCH S. A molecular dynamics study of WPD-loop flexibility in PTP1B Biochemical and Biophysical Research Communications 356 (4) , 1011 - 101 doi: 10.1016/j.bbrc.2007.03.093

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