Inka Sastalla's profile

What I do

Currently, I am working as a postdoc fellow at the National Institutes of Health in Bethesda, Maryland. I am one of the lucky ones to work in the brand-new building on campus, Bldg 33. My scientific background is bacterial pathogenesis and I did my PhD at the German Research Center for Biotechnology in Braunschweig, Germany (now Helmholtz Center for Infection Research, HZI)on Streptococcus pyogenes. Currently, I am working on Bacillus anthracis here at the Lab of Bacterial Disease.

Affiliations

Current

Location

City:
None chosen
Hub:
None chosen

Interests

Not only bacterial pathogenesis, but in general all biology-related topics… there are too many to list them all.

Projects

Bacterial infection modelling
Bacterial mutagenesis
Gene reporter systems

Publications

  • Dinkla K, Sastalla I, Godehardt A, Janze N, Chhatwal G, Rohde M, Medina E. Upregulation of capsule enables Streptococcus pyogenes to evade immune recognition by antigen-specific antibodies directed to the G-related alpha2-macroglobulin-binding protein GRAB located on the bacterial surface. Microbes and infection / Institut Pasteur 9 (8) , 922-31 (2007) (Epub 06 Apr 2007) PubMed ID:(17544803)

  • Linge H, Sastalla I, Nitsche-Schmitz D, Egesten A, Frick I. Protein FOG is a moderate inducer of MIG/CXCL9, and group G streptococci are more tolerant than group A streptococci to this chemokine's antibacterial effect. Microbiology (Reading, England) 153 (Pt 11) , 3800-8 (2007) PubMed ID:(17975089)

  • Nitsche-Schmitz D, Johansson H, Sastalla I, Reissmann S, Frick I, Chhatwal G. Group G streptococcal IgG binding molecules FOG and protein G have different impacts on opsonization by C1q. The Journal of biological chemistry 282 (24) , 17530-6 (2007) (Epub 20 Apr 2007) PubMed ID:(17449474 )

  • Siegert J, Sastalla I, Chhatwal G, Medina E. Vaccination equally enables both genetically susceptible and resistant mice to control infection with group A streptococci. Microbes and infection / Institut Pasteur 8 (2) , 347-53 (2006) (Epub 13 Sep 2005) PubMed ID:(16213175)

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