Julio Saez-Rodriguez's profile
What I do
I am postdoctoral fellow at Harvard Medical School, Department of Systems Biology, and Massachusetts Institute of Technology, Department of Bioengineering.
I work on the mathematical analysis of signaling networks. More information here
Affiliations
Current affiliations
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- Position
- Research Fellow
- Company
- Harvard Medical School/ M.I.T.
- Further information
Past affiliations
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- Position
- Research Assistant
- Company
- Max-Planck-institute for the Dynamics of Complex Technial Systems, Systems Biology Group
- Duration
- 2002 - 2007
- Further information
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- Position
- Assistant
- Company
- Institute of Biochemical Engineering, University of Stuttgart
- Duration
- 2001 - 2002
- Further information
Location
- City:
- None chosen
- Hub:
- Boston
Interests
I am interested in understanding how signaling networks in mammalian cells are able to decode multifarious signals, and how they are impaired in cancerous cells. You can find more details here
Projects
Construction of context-specific maps of signaling networks and executable discrete models using high-throughput data. Case studies: normal vs. cancerous hepatocytes and breast cancer cell lines
Methods and software to link high-throughput experimental data and models
Publications
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Flexible Informatics for Linking Experimental Data to Mathemati-cal Models via DataRail. (2008) (Epub 24 Jan 2008) PubMed ID:(18218655)
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Klamt S, Saez-Rodriguez J, Gilles E. Structural and functional analysis of cellular networks with CellNetAnalyzer. BMC systems biology , 2 (2007) (Epub 08 Jan 2007) PubMed ID:(17408509)
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Kremling A, Saez-Rodriguez J. Systems biology--an engineering perspective. Journal of biotechnology (2) , 329-51 (2007) (Epub 24 Feb 2007) PubMed ID:(17400319)
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Saez-Rodriguez J, Simeoni L, Lindquist J, Hemenway R, Bommhardt U, Arndt B, Haus U, Weismantel R, Gilles E, Klamt S, Schraven B. A logical model provides insights into T cell receptor signaling. PLoS computational biology (8) , e163 (2007) (Epub 05 Jul 2007) PubMed ID:(17722974 )
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Conzelmann H. Saez-Rodriguez J. Sauter T. Kholodenko BN. Gilles ED.. A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks BMB Bioinformatics (2006)
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