• Nikolaus Oberprieler's profile

    • What I do

      At present I am conducting research on PKA signalling networks, including A-kinase anchoring protein complex composition. I am more generally interested in intra-cellular signalling events and I now work on primary T-cells, but have previously worked on platelets and endothelial cells.

      Blog:
      Science at random

    • Affiliations

      Current

    • Interests

      I am primarily interested in PKA signalling networks and PKA/AKAP signalosomes. Before starting my postdoc, I was interested in the effects of nitric oxide on integrin signalling in platelets and I am now looking at the application of my previous research on T-cell signalling.

    • Projects

      Nikolaus Oberprieler has not yet listed any projects.

    • Publications

      • Milward A, Riba R, Patel B, Oberprieler N, Naseem K. Sodium orthovanadate induced tyrosine phosphorylation of platelet nitric oxide synthase negatively regulates enzyme activity. Biochimica et biophysica acta 1760 (9) , 1411-7 (Epub 17 Jun 2006) PubMed ID:(16875784)

      • Oberprieler N, Roberts W, Graham A, Homer-Vanniasinkam S, Naseem K. Inhibition of ADP-induced platelet adhesion to immobilised fibrinogen by nitric oxide: evidence for cGMP-independent mechanisms. Biochemical pharmacology 73 (10) , 1593-601 (Epub 14 Jan 2007) PubMed ID:(17306768)

      • Oberprieler N, Roberts W, Riba R, Graham A, Homer-Vanniasinkam S, Naseem K. cGMP-independent inhibition of integrin alphaIIbbeta3-mediated platelet adhesion and outside-in signalling by nitric oxide. FEBS letters 581 (7) , 1529-34 (Epub 07 Mar 2007) PubMed ID:(17376438)

      • Patel B, Sharifi M, Milward A, Oberprieler N, Gibbins J, Parkin S, Naseem K. Platelet nitric oxide synthase is activated by tyrosine dephosphorylation: possible role for SHP-1 phosphatase. Journal of thrombosis and haemostasis : JTH 4 (11) , 2423-32 (Epub 08 Aug 2006) PubMed ID:(16898954)

      • Riba R, Oberprieler N, Roberts W, Naseem K. Von Willebrand factor activates endothelial nitric oxide synthase in blood platelets by a glycoprotein Ib-dependent mechanism. Journal of thrombosis and haemostasis : JTH 4 (12) , 2636-44 PubMed ID:(17100655)

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    • Contact

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