Aneesh Panoli's profile

I'm male

What I do

I am working on the molecular biology of meiosis, recombination in particular, in Arabidopsis at Centre for Cellular and Molecular Biology, Hyderabad, India.

The work in our lab is mainly focused on the identification and characterization of genes that control meiosis.

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Interests

Crack the code of Meiosis.

Meiosis is considered to be one of the most specialized cell division in our body that gives rise to gametes.

The most interesting thing about meiosis is that not all the cells in the body can perform meiosis. Again there are differences, in budding yeast every diploid vegetative cell has the potential to undergo meiosis, where as in higher plants only a subset of them carry out meiosis. In mammals its still specialized where during the embryogenesis itself a group of cells are set aside for this specific purpose.

Now the important question comes…
Whats converts a mitotic cell to meiotic cell? In yeast its nutrition ..the IME class of the genes are the master regulators. in plants, still we are not sure what really triggers this fascinating conversion. In mammals its hormones, partly, and the rest still remains in dark.

Is it possible to induce a mammalian cell or a plant cell in culture to undergo meiosis? the answer is NO?
Why …? Because we know nothing…!!!

Projects

  1. Control of meiosis in plants.
  2. study of conservation of meiotic genes between yeast and plants.

Publications

Aneesh Panoli's activity on Nature Network

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