Liming Liang's profile

I'm male

What I do

I’m a Ph.D. student working with Goncalo Abecasis at the University of Michigan. My research is focused on developing the computational and statistical tools required for understanding human genetic variation, with a particular focus on complex human disease.

Location

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Interests

Research projects currently focus on the genetic matching for case-control samples, whole genome simulator, genetics of asthma and whole-genome association study of global gene expression.

Projects

  • Genotype-based matching to correct for population stratification in large-scale case-control association Studies.
  • Genome-wide association mapping for genetics of asthma.
  • Whole-genome association mapping of global gene expression.
  • Coalescent-based whole genome simulator

Publications

  • Li M, Atmaca-Sonmez P, Othman M, Branham K, Khanna R, Wade M, Li Y, Liang L, Zareparsi S, Swaroop A, Abecasis G. CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration Nat Genet 38 (9) , 1049 - 105 (Epub 27 Aug 2006) doi: 10.1038/ng1871

  • Liang L, Zollner S, Abecasis G. GENOME: a rapid coalescent-based whole genome simulator Bioinformatics 23 (12) , 1565 - 156 (Epub 25 Apr 2007) doi: 10.1093/bioinformatics/btm138

  • Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, Vermeire S, Dewit O, de Vos M, Dixon A, Demarche B, Gut I, Heath S, Foglio M, Liang L, Laukens D, Mni M, Zelenika D, Gossum A, Rutgeerts P, Belaiche J, Lathrop M, Georges M. Novel Crohn Disease Locus Identified by Genome-Wide Association Maps to a Gene Desert on 5p13.1 and Modulates Expression of PTGER4 PLoS Genet 3 (4) doi: 10.1371/journal.pgen.0030058

  • Moffatt M, Kabesch M, Liang L, Dixon A, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen S, Wong K, Illig T, Vogelberg C, Weiland S, von Mutius E, Abecasis G, Farrall M, Gut I, Lathrop G, Cookson W. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma Nature 448 (7152) , 470 - 473 (Epub 04 Jul 2007) doi: 10.1038/nature06014

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