Kay Hofmann's profile
What I do
Affiliations
Current affiliations
-
- Position
- Head of Bioinformatics
- Company
- Miltenyi Biotec GmbH
- Further information
Location
- City:
- Köln, North Rhine-Westphalia, Germany
- Hub:
- Cologne
Interests
1) Trying to understand the function of the ubiquitin proteasome system and its components, mainly by application of bioinformatics.
2) Techniques for protein function prediction from sequence and high-throuput data sources.
3) Modular architecture of multi-domain proteins
Projects
Kay Hofmann has not yet listed any projects.
Publications
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Activating the ubiquitin family: UBA6 challenges the field. Trends in biochemical sciences (2008) (Epub 17 Mar 2008) PubMed ID:(18353650)
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Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature (7194) , 481-488 (2008) PubMed ID:(18497817)
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The Yeast GID Complex, a Novel Ubiquitin Ligase (E3) Involved in the Regulation of Carbohydrate Metabolism. Molecular biology of the cell (2008) (Epub 04 Jun 2008) PubMed ID:(18508925 )
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Hoyt M, McDonough S, Pimpl S, Scheel H, Hofmann K, Coffino P. A genetic screen for Saccharomyces cerevisiae mutants affecting proteasome function, using a ubiquitin-independent substrate. Yeast (Chichester, England) (3) , 199-217 (2008) PubMed ID:(18260085)
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Komander D, Lord C, Scheel H, Swift S, Hofmann K, Ashworth A, Barford D. The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module. Molecular cell (4) , 451-64 (2008) PubMed ID:(18313383)
Contact
- email:
- kay.hofmann [ at ] miltenyibiotec.de
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