partha chakrabarti's profile
What I do
I’m a medical doctor by training and currently in Phd program of ‘cell and molecular biology’ at boston university. broad field of my research is diabetes/obesity and in particular study of molecular sensors of energy availability/deprivation.
Other than science, I’m interested in Philosophy of science.
Affiliations
Current affiliations
-
- Position
- graduate student
- Company
- Boston University School of Medicine
- Further information
Location
- City:
- None chosen
- Hub:
- Boston
Interests
1.understand the functional complexities of molecular sensors (AMPK, mTORC1,FoxO, Sirtuins etc)of energy/nutrition availability.
2. philosophy of science, especially philosophy of biology (popper, feyerabend, gould, lewontin, fox-keller, bruno latour)
Projects
1. mTORC1-dependent translational regulation of leptin biosynthesis.
2. transcriptional regulation of fat accumulation via insulin/Akt/FoxO signaling axis.
3.fatty acid signaling and its implications in diabetes.
Publications
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The mTOR complex 1 regulates leptin biosynthesis in adipocytes at the level of translation. The role of the 5'-UTR in the expression of leptin mRNA. Molecular endocrinology (Baltimore, Md.) (2008) (Epub 24 Jul 2008) PubMed ID:(18653778)
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Gupta R, Chakrabarti P, Dikshit M, Dash D.. Late signaling in the activated platelets upregulates tyrosine phosphatase SHP1 and impairs platelet adhesive functions: Regulation by calcium and Src kinase Biochim Biophys Acta. , 131-40 (2007)
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Chakrabarti P, Dash D, Panda BK.. Detection of Ggamma(Agammadeltabeta)0 thalassemia in North India Clin Chim Acta , 363-4 (2006)
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Chakrabarti P, Gupta R, Mishra A, Rai M, Singh VP, Dash D.. Spectrum of beta-thalassemia mutations in North Indian states: a beta-thalassemia trait with two mutations in cis Clin Biochem , 576-8 (2005 )
Contact
- email:
- partha [ at ] bu.edu
- Yahoo:
- partha_chakraborty2000@yahoo.com
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