John Hogenesch's profile
What I do
Affiliations
Current affiliations
-
- Position
- Associate Professor
- Company
- University of Pennsylvania School of Medicine
- Duration
- 2006 - Present
- Further information
Past affiliations
-
- Position
- Professor
- Company
- The Scripps Research Institute
- Duration
- 2004 - 2006
-
- Position
- Assistant Professor
- Company
- The Scripps Research Institute
- Duration
- 2003 - 2004
Location
- City:
- Philadelphia, Pennsylvania, United States
- Hub:
- Philadelphia
Interests
Our research program covers two areas of research, the biology of circadian clocks in mammals, and the genome wide application of functional genomics tools. Key questions being approached in circadian research include the composition and mechanisms of the core oscillator, as well as the methods by which the clock dictates rhythms in physiology and behavior. The systems biology paradigm of perturb, observe, model, and test is being used to elucidate the network properties of the circadian clock. Functional genomics methods are being developed and utilized in the lab to inform the circadian system, but can also be more broadly applied to other areas of mammalian cell biology. By conducting research in two complementary areas, we hope to contribute to a better understanding of circadian biology, as well as contribute to other areas of cell signaling research.
Projects
John Hogenesch has not yet listed any projects.
Publications
-
Amelio A, Miraglia L, Conkright J, Mercer B, Batalov S, Cavett V, Orth A, Busby J, Hogenesch J, Conkright M. A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway. Proceedings of the National Academy of Sciences of the United States of America (51) , 20314-9 (2007) (Epub 11 Dec 2007) PubMed ID:(18077367)
-
Hughes M, Deharo L, Pulivarthy S, Gu J, Hayes K, Panda S, Hogenesch J. High-resolution time course analysis of gene expression from pituitary. Cold Spring Harbor symposia on quantitative biology , 381-6 (2007) PubMed ID:(18419295)
-
Su A, Hogenesch J. Power-law-like distributions in biomedical publications and research funding. Genome biology (4) , 404 (2007) PubMed ID:(17472739)
-
Sato T, Yamada R, Ukai H, Baggs J, Miraglia L, Kobayashi T, Welsh D, Kay S, Ueda H, Hogenesch J. Feedback repression is required for mammalian circadian clock function. Nature genetics (3) , 312-9 (2006) (Epub 12 Feb 2006) PubMed ID:(16474406)
-
Willingham A, Orth A, Batalov S, Peters E, Wen B, Aza-Blanc P, Hogenesch J, Schultz P. A strategy for probing the function of noncoding RNAs finds a repressor of NFAT. Science (New York, N.Y.) (5740) , 1570-3 (2005) PubMed ID:(16141075)
Contact
- email:
- hogenesc [ at ] mail.med.upenn.edu
John Hogenesch's activity on Nature Network
Entries
There are no recent entries from John Hogenesch.