Francesco Lotti's profile
What I do
Interested to the characterization of the molecular functions of the SMN (Survival of motor neurons) protein complex and to define its role in the motor neuron degenerative disease Spinal Muscular Atrophy (SMA).
PrometeoNetwork co-founder (www.prometeonetwork.com)
Affiliations
Current affiliations
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- Position
- Postdoc
- Company
- Columbia University
- Further information
Past affiliations
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- Position
- HHMI-Research Associate
- Company
- University of Pennsylvania
- Duration
- 2003 - 2007
- Further information
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- Position
- PhD Student
- Company
- DIBIT-Ospedale San Raffaele
- Duration
- 1999 - 2003
- Further information
Location
- City:
- None chosen
- Hub:
- None chosen
Interests
No interests have been listed by Francesco Lotti.
Projects
Francesco Lotti has not yet listed any projects.
Publications
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Battle D, Kasim M, Yong J, Lotti F, Lau C, Mouaikel J, Zhang Z, Han K, Wan L, Dreyfuss G. The SMN complex: an assembly machine for RNPs. Cold Spring Harbor symposia on quantitative biology , 313-20 (2006) PubMed ID:(17381311 )
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Battle D, Lau C, Wan L, Deng H, Lotti F, Dreyfuss G. The Gemin5 protein of the SMN complex identifies snRNAs. Molecular cell (2) , 273-9 (2006) PubMed ID:(16857593)
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Menegon A, Bonanomi D, Albertinazzi C, Lotti F, Ferrari G, Kao H, Benfenati F, Baldelli P, Valtorta F. Protein kinase A-mediated synapsin I phosphorylation is a central modulator of Ca2+-dependent synaptic activity. The Journal of neuroscience : the official journal of the Society for Neuroscience (45) , 11670-81 (2006) PubMed ID:(17093089)
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Urbinati F, Lotti F, Facchini G, Montanari M, Ferrari G, Mavilio F, Grande A. Competitive engraftment of hematopoietic stem cells genetically modified with a truncated erythropoietin receptor. Human gene therapy (5) , 594-608 (2005) PubMed ID:(15916484)
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Testa A, Lotti F, Cairns L, Grande A, Ottolenghi S, Ferrari G, Ronchi A. Deletion of a negatively acting sequence in a chimeric GATA-1 enhancer-long terminal repeat greatly increases retrovirally mediated erythroid expression. The Journal of biological chemistry (11) , 10523-31 (2004) (Epub 29 Dec 2003) PubMed ID:(14701820 )
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