Elizabeth Tunbridge's profile

What I do

My research uses a multidisciplinary approach to understand how genes impact on brain function, and how they can modulate risk for psychiatric disorders, focussing in particular on the catechol-O-methyltransferase gene.

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Interests

The biological basis of psychiatric disorders
Understanding how genes impact on behaviour
Dopaminergic control of brain function

Projects

Elizabeth Tunbridge has not yet listed any projects.

Publications

  • Polymorphisms in the catechol-O-methyltransferase (COMT) gene influence plasma total homocysteine levels. (2008) (Epub 11 Jan 2008) PubMed ID:(18189241)

  • Catechol-O-Methyltransferase (COMT): A Gene Contributing to Sex Differences in Brain Function, and to Sexual Dimorphism in the Predisposition to Psychiatric Disorders. (2007) (Epub 05 Sep 2007) PubMed ID:(17805313)

  • Sei Y, Ren-Patterson R, Li Z, Tunbridge E, Egan M, Kolachana B, Weinberger D. Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms. Molecular psychiatry 12 (10) , 946-57 (2007) (Epub 17 Apr 2007) PubMed ID:(17440436)

  • Tunbridge E, Lane T, Harrison P. Expression of multiple catechol-o-methyltransferase (COMT) mRNA variants in human brain. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 144 (6) , 834-9 (2007) PubMed ID:(17477346)

  • Tunbridge E, Weickert C, Kleinman J, Herman M, Chen J, Kolachana B, Harrison P, Weinberger D. Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan. Cerebral cortex (New York, N.Y. : 1991) 17 (5) , 1206-12 (2007) (Epub 11 Jul 2006) PubMed ID:(16835293)

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