Ellen Fritsche's profile

What I do

My research focus lies on the investigation of effects that exogenous noxae exert on cells. These include UV radiation, persisent organic chemicals and metals. In particular, keratinocytes and brain cells are the center of attention in my group.

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Interests

UV signal transduction
aging
arylhydrocarbon receptor
alternative methods
developmental neurotoxicity
neurotoxicity

Projects

Ellen Fritsche has not yet listed any projects.

Publications

  • Fritsche E, Schafer C, Calles C, Bernsmann T, Bernshausen T, Wurm M, Hubenthal U, Cline J, Hajimiragha H, Schroeder P, Klotz L, Rannug A, Furst P, Hanenberg H, Abel J, Krutmann J. Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation Proceedings of the National Academy of Sciences 104 (21) , 8851 - 8856 (2007) doi: 10.1073/pnas.0701764104

  • Haarmann-Stemmann T, Bothe H, Kohli A, Sydlik U, Abel J, Fritsche E. Analysis of the Transcriptional Regulation and Molecular Function of the Aryl Hydrocarbon Receptor Repressor in Human Cell Lines Drug Metabolism and Disposition 35 (12) , 2262 - 2269 (2007) (Epub 04 Sep 2007) doi: 10.1124/dmd.107.016253

  • MOORS M, CLINE J, ABEL J, FRITSCHE E. ERK-dependent and -independent pathways trigger human neural progenitor cell migration Toxicology and Applied Pharmacology 221 (1) , 57 - 67 (2007) doi: 10.1016/j.taap.2007.02.018

  • Fritsche E, Cline J, Nguyen N, Scanlan T, Abel J. PCBs Disturb Differentiation of Normal Human Neural Progenitor Cells: Clue for Involvement of Thyroid Hormone Receptors Environ. Health Perspect. (2005) doi: 10.1289/ehp.7793

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