Mary Kushman's profile
What I do
Postdoctoral research fellow in pharmacology and toxicology, focusing on metabolism of polycyclic aromatic hydrocarbons.
Affiliations
Current affiliations
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- Position
- Postdoctoral Fellow
- Company
- University of Pennsylvania
Location
- City:
- Philadelphia, Pennsylvania, United States
- Hub:
- Philadelphia
Interests
My main research interests are in the biological effects of the metabolites of polycyclic aromatic hydrocarbons, including but not limited to: enzymology of CYP450s, GSTs, and aldo-keto reductases, mass spectral characterization of PAH metabolites and their macromolecular adducts.
Projects
Mary Kushman has not yet listed any projects.
Publications
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Kushman M, Kabler S, Ahmad S, Doehmer J, Morrow C, Townsend A. Cytotoxicity and mutagenicity of dibenzo[a,l]pyrene and (+/-)-dibenzo[a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione-S-transferase A1. Mutation research (1-2) , 80-7 (2007) (Epub 19 Apr 2007) PubMed ID:(17509623)
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Kushman M, Kabler S, Ahmad S, Doehmer J, Morrow C, Townsend A. Protective efficacy of hGSTM1-1 against B[a]P and (+)- or (-)-B[a]P-7,8-dihydrodiol cytotoxicity, mutagenicity, and macromolecular adducts in V79 cells coexpressing hCYP1A1. Toxicological sciences : an official journal of the Society of Toxicology (1) , 51-7 (2007) (Epub 24 May 2007) PubMed ID:(17525473 )
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Kushman M, Kabler S, Fleming M, Ravoori S, Gupta R, Doehmer J, Morrow C, Townsend A. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP Carcinogenesis (1) , 207-14 (2007) (Epub 02 Aug 2006) PubMed ID:(16885195)
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