Boris Cvek's profile
I'm male and 32
What I do
2003 founder of on-line magazine TEMA focused on literary criticism
2004 teacher at basic and grammar schools
since 2004 political writer and publicist
2006 PhD in Coordination Chemistry, Ni(II) dithiocarbamates
since 2006 research in proteasome and NF-kB inhibition, the main idea: disulfiram as future drug in cancer therapy
since 2007 PhD student in philosophy of science (at Charles University in Prague), my mentor
Affiliations
Current affiliations
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- Position
- researcher and teacher
- Company
- Palacky University, Olomouc, Czech Republic
- Further information
Location
- City:
- None chosen
- Hub:
- None chosen
Interests
Anything about proteasome or NF-kB. Molecular oncology. Coordination chemistry. Philosophy of science (especially Dewey´s instrumentalism in the context of newer philosophy of Feyerabend, Sellars, Putnam, van Fraassen, Rorty, Quine...).
Projects
postdoc grant (Czech Science Foundation): Influence of dithiocarbamate complexes with Pt(II) and Au(III) on NF-kB pathway in human tumor lines HepG2 and SK-HEP-1.
Publications
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Cvek B. TNF-alpha could be responsible for disulfiram-mediated hepatotoxicity (Letter to Editor) Journal of Hepatology (2008)
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Cvek B and Dvorak Z. The value of proteasome inhibition in cancer. Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor? Drug Discovery Today , 716-722 (2008)
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Cvek B and Dvorak Z. Targeting of Nuclear Factor-kappaB and Proteasome by Dithiocarbamate Complexes with Metals. Current Pharmaceutical Design , 3155-3167 (2007)
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Cvek B, Dvorak Z, Taraba J, Muller L, Vrzal R, Ulrichova J. Opposite effects of two zinc(II) dithiocarbamates on NF-kB pathway. Available from Nature Precedings. (2007)
Boris Cvek's activity on Nature Network
Entries
In the last week:
posted comment It’s not just knowing your ...
posted comment Moreover… from yester...
posted comment Mark: Maybe I should return...
posted comment Excatly, Mark :) Two papers...
posted comment Henry, I think this guy wou...
posted comment As Tom Lehrer noted, the re...
posted comment Boris – what an interesting...
posted comment There are many promising an...
posted comment Thanks, Henry. In my view, ...
posted comment Hi David, I have watched th...
posted comment Stephen: Maybe we can get o...
posted comment RICHARD As I keep saying...
posted comment That was the old age of sci...
posted comment Where are you? – the cynics...
posted comment I agree, Stephen.