Marco Cosentino's profile

I'm male

What I do

  • Clinical pharmacology: pharmacogenetics, Therapeutic Drug Monitoring, clinical trials;
  • Pharmacoepidemiology;
  • Pharmacovigilance;
  • Phytomedicine.

Location

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Interests

Basic and translational research interests: pharmacology of neuroimmunomodulation, nervous system-immune system interactions (in particular adrenergic and dopaminergic mechanisms and their clinical relevance in neurological disorders, anti-tumor response, autoimmunity, immune tolerance). Present studies are taking into account the physiopharmacology of the intrinsic dopaminergic/adrenergic system of human lymphocytes and its involvement in disease such as multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, Tourette’s syndrome, and other neural and psychiatric disorders.

Further interests concern neuro- and immunopharmacology, including the effects of CNS drugs on the immune response and the screening of new candidate drugs for their effects on the nervous system and/or on the immune system.

A recently established research area regards the pharmacology of herbs and herbal drugs, in the context of an International Collaborative Network involving the University of Insubria (I), the University of Heidelberg (D), the University of Zurich (CH), the Haute Ecole Valaisanne (CH), the Alpine Institute for Phytopharmacology (CH).

Projects

Marco Cosentino has not yet listed any projects.

Publications

  • Cosentino M, Fietta A, Ferrari M, Rasini E, Bombelli R, Carcano E, Saporiti F, Meloni F, Marino F, Lecchini S. Human CD4+CD25+ regulatory T cells selectively express tyrosine hydroxylase and contain endogenous catecholamines subserving an autocrine/paracrine inhibitory functional loop. Blood 109 (2) , 632-42 (2007) (Epub 19 Sep 2006) PubMed ID:(16985181)

  • Cosentino M, Marino F, Ferrari M, Rasini E, Bombelli R, Luini A, Legnaro M, Canne M, Luzzani M, Crema F, Paracchini S, Lecchini S. Estrogenic activity of 7-hydroxymatairesinol potassium acetate (HMR/lignan) from Norway spruce (Picea abies) knots and of its active metabolite enterolactone in MCF-7 cells. Pharmacological research : the official journal of the Italian Pharmacological Society 56 (2) , 140-7 (2007) (Epub 22 May 2007) PubMed ID:(17572100)

  • Guasti L, Marino F, Cosentino M, Cimpanelli M, Piantanida E, Mainardi L, Vanoli P, De Palma D, Bombelli R, Ferrari M, Crespi C, Simoni C, Klersy C, Gaudio G, Maroni L, Grandi A, Tanda M, Bartalena L, Cerutti S, Lecchini S, Venco A. Changes in autonomic modulation to the heart and intracellular catecholamines. A longitudinal study in differentiated thyroid carcinoma during short-term hypothyroidism and thyroid hormone replacement. Hormone research 67 (4) , 171-8 (2007) (Epub 13 Nov 2006) PubMed ID:(17106203)

  • Marino F, Guasti L, Cosentino M, Ferrari M, Rasini E, Maio R, Cimpanelli M, Cereda E, Crespi C, Simoni C, Restelli D, Venco A, Lecchini S. Angiotensin II type 1 receptor expression in polymorphonuclear leukocytes from high-risk subjects: changes after treatment with simvastatin. Journal of cardiovascular pharmacology 49 (5) , 299-305 (2007) PubMed ID:(17513949)

  • Guasti L, Marino F, Cosentino M, Cimpanelli M, Maio R, Klersy C, Crespi C, Restelli D, Simoni C, Franzetti I, Gaudio G, Marnini P, Grandi A, Lecchini S, Venco A. Simvastatin treatment modifies polymorphonuclear leukocyte function in high-risk individuals: a longitudinal study. Journal of hypertension 24 (12) , 2423-30 (2006) PubMed ID:(17082725)

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