Asif Khan's profile
I'm male and 28
What I do
I am a graduate student at the Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore. My research interests are in the characterization and analysis of targets of immune responses in viruses, and their applications in the area of computer-aided vaccine research. I have developed a novel bioinformatics methodology for systematic screening and selection of targets of immune responses that are candidates for formulation of vaccines against viruses. I have applied the methodology to dengue virus sequence data to screen and select for candidate immunogens that are effective against broad spectrum of the virus and are applicable to a large proportion of the human population. We are, currently, experimentally validating these candidate immunoges with our collaborators from Johns Hopkins University, USA.
Affiliations
Current affiliations
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- Position
- Graduate Student
- Company
- National University of Singapore
- Further information
Location
- City:
- None chosen
- Hub:
- None chosen
Interests
Bioinformatics, Immunoinformatics, immunomics, computer-aided vaccine design, molecular biology
Projects
Asif Khan has not yet listed any projects.
Publications
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Sangket U, Phongdara A, Chotigeat W, Nathan D, Kim W, Bhak J, Ngamphiw C, Tongsima S, Khan A, Lin H, Tan T. Automatic synchronization and distribution of biological databases and software over low-bandwidth networks among developing countries. Bioinformatics (Oxford, England) (2) , 299-301 (2008) (Epub 23 Nov 2007) PubMed ID:(18037613)
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Heiny A, Miotto O, Srinivasan K, Khan A, Zhang G, Brusic V, Tan T, August J. Evolutionarily conserved protein sequences of influenza a viruses, avian and human, as vaccine targets. PLoS ONE (11) , e1190 (2007) (Epub 21 Nov 2007) PubMed ID:(18030326)
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Khan A, Heiny A, Lee K, Srinivasan K, Tan T, August J, Brusic V. Large-scale analysis of antigenic diversity of T-cell epitopes in dengue virus. BMC bioinformatics , S4 (2006) (Epub 18 Dec 2006) PubMed ID:(17254309)
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Khan A, Miotto O, Heiny A, Salmon J, Srinivasan K, Nascimento E, Marques E, Brusic V, Tan T, August J. A systematic bioinformatics approach for selection of epitope-based vaccine targets. Cellular immunology (2) , 141-7 (2006) (Epub 16 Apr 2007) PubMed ID:(17434154)
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Zhang G, Khan A, Srinivasan K, August J, Brusic V. MULTIPRED: a computational system for prediction of promiscuous HLA binding peptides. Nucleic acids research (Web Server issue) , W172-9 (2005) PubMed ID:(15980449)
Contact
- email:
- me.asifkhan [ at ] gmail.com
- MSN:
- sci91078@hotmail.com
- Skype:
- sci91078
Asif Khan's activity on Nature Network
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