Anni-Maija Linden's profile
I'm female
What I do
I’m studying metabotropic glutamate receptoros and how they modulate neuronal circuitries and behaviors relevant for neuropsychiatric disorders such as anxiety and schizophrenia.
Affiliations
Current affiliations
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- Position
- Researcher, Lecturer
- Company
- University of Helsinki
- Further information
Location
- City:
- None chosen
- Hub:
- None chosen
Interests
Brain regions and neuronal networks which are important for mediating therapeutically beneficial effects of anxiolytic and antipsychotic drugs.
Projects
Regionally distinct roles of mGlu2 vs. mGlu3 receptors in modulation of neuronal activity in mouse brain
Publications
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Linden A, Sandu C, Aller M, Vekovischeva O, Rosenberg P, Wisden W, Korpi E. TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics. The Journal of pharmacology and experimental therapeutics (3) , 924-34 (2007) (Epub 17 Sep 2007) PubMed ID:(17875609)
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Linden A, Baez M, Bergeron M, Schoepp D. Effects of mGlu2 or mGlu3 receptor deletions on mGlu2/3 receptor agonist (LY354740)-induced brain c-Fos expression: specific roles for mGlu2 in the amygdala and subcortical nuclei, and mGlu3 in the hippocampus. Neuropharmacology (2) , 213-28 (2006) (Epub 02 Jun 2006) PubMed ID:(16733060)
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Linden A, Bergeron M, Schoepp D. Comparison of c-Fos induction in the brain by the mGlu2/3 receptor antagonist LY341495 and agonist LY354740: evidence for widespread endogenous tone at brain mGlu2/3 receptors in vivo. Neuropharmacology , 120-34 (2005) PubMed ID:(16023151)
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