Marcelo Febo's profile
I'm male
What I do
Affiliations
Current affiliations
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- Position
- Assistant Professor
- Company
- Northeastern University
- Further information
Location
- City:
- None chosen
- Hub:
- Boston
Interests
The broad objective of our laboratory is to characterize neuronal and behavioral changes that occur with repeated exposure to drugs of abuse. Currently, we are interested in studying the dopaminergic system in the maternal brain and its role in processing rewarding stimuli. Lactation provides a rewarding experience beneficial to mother-infant bonding. Cocaine addiction can sever this critical mother-infant experience, possibly affecting child psychosocial development. A host of methodologies from functional MRI, in vivo neuronal recordings to in vivo microdialysis and receptor autoradiography are being applied to identify and characterize neural networks activated by suckling and other pup-derived sensory stimuli that represent natural rewards for lactating rats.
Projects
Brain Imaging of Cocaine and Maternal Reward.
Publications
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Febo M, Ferris C. Development of cocaine sensitization before pregnancy affects subsequent maternal retrieval of pups and prefrontal cortical activity during nursing. Neuroscience (2) , 400-12 (2007) (Epub 25 Jul 2007) PubMed ID:(17651902)
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Ferris C, Febo M, Luo F, Schmidt K, Brevard M, Harder J, Kulkarni P, Messenger T, King J. Functional magnetic resonance imaging in conscious animals: a new tool in behavioural neuroscience research. Journal of neuroendocrinology (5) , 307-18 (2006) PubMed ID:(16629829)
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Schmidt K, Febo M, Shen Q, Luo F, Sicard K, Ferris C, Stein E, Duong T. Hemodynamic and metabolic changes induced by cocaine in anesthetized rat observed with multimodal functional MRI. Psychopharmacology (4) , 479-86 (2006) (Epub 21 Mar 2006) PubMed ID:(16550388)
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Febo M, Ferris C, Segarra A. Estrogen influences cocaine-induced blood oxygen level-dependent signal changes in female rats. The Journal of neuroscience : the official journal of the Society for Neuroscience (5) , 1132-6 (2005) PubMed ID:(15689549)
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Febo M, Numan M, Ferris C. Functional magnetic resonance imaging shows oxytocin activates brain regions associated with mother-pup bonding during suckling. The Journal of neuroscience : the official journal of the Society for Neuroscience (50) , 11637-44 (2005) PubMed ID:(16354922)
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