Stephen Lee's profile

What I do

Affiliations

Current

Past

Location

City:
Vancouver, British Columbia, Canada
Hub:
Vancouver

Interests

A life outside the lab?!? When I decide that work-life balance may be feasible I go trail running, play beach volleyball poorly, and try to check out live music as often as possible.

Projects

I’m looking at the molecular mechanisms potentially involved in the absorption of cholesterol from the intestinal lumen.

Publications

  • Wasan K, Brocks D, Lee S, Sachs-Barrable K, Thornton S. Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery Nat Rev Drug Discov 7 (1) , 84 - 99 (2008) doi: 10.1038/nrd2353

  • Wasan K, Risovic V, Sivak O, Lee S, Mason D, Chiklis G, McShane J, Lynn M, Wong N, Rossignol D. Influence of Plasma Cholesterol and Triglyceride Concentrations and Eritoran (E5564) Micelle Size on its Plasma Pharmacokinetics and Ex Vivo Activity Following Single Intravenous Bolus Dose Into Healthy Female Rabbits Pharm Res 25 (1) , 176 - 182 (2008) (Epub 12 Sep 2007) doi: 10.1007/s11095-007-9428-8

  • BABUDHANIKULA A, MOHAMEDKHALID N, LEE S, YEUNG R, RISOVIC V, WASAN K, LEROUX J. Long circulating lipid nanocapsules for drug detoxification Biomaterials 28 (6) , 1248 - 1257 (2007) doi: 10.1016/j.biomaterials.2006.10.036

  • Shayeganpour A, Lee S, Wasan K, Brocks D. The Influence of Hyperlipoproteinemia on in Vitro Distribution of Amiodarone and Desethylamiodarone in Human and Rat Plasma Pharm Res 24 (4) , 672 - 678 (2007) (Epub 15 Feb 2007) doi: 10.1007/s11095-006-9186-z

  • Lee S, Wasan K, Calcagni A, Avery M, McCush F, Chen C. The in Vitro Plasma Distribution of a Novel Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, Is Influenced by Differences in Plasma Lipid Concentrations Pharm Res 23 (5) , 1025 - 1030 (2006) (Epub 04 May 2006) doi: 10.1007/s11095-006-9908-2

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