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Junwang Xu's profile
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What I do
cardiac hypertrophy, vascular disease, animal model, heart development, cardiac physiology, Neurofibromatosis type I
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Affiliations
Current affiliations
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- Position
- Postdoctoral Researcher in Dr. Jon Epstein's lab
- Company
- University of Pennsylvania
Past affiliations
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- Position
- Postdoctoral Researcher
- Company
- New Jersry Medical School, UMDNJ
- Duration
- 2003 - 2005
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Interests
I am working in the area of cardiac hypertrophy, specifically examining cardiac specific knock out NF1 gene in mouse model. I am interest in signaling pathway related to cardiac hypertrophy, drug that can prevent cardiac hypertrophy, and various cardiac hypertrophy animal model.
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Projects
animal model, cardiac specific knockout Nf1 gene
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Publications
Xu J, Ismat FA, Wang T, Yang J, Epstein JA. NF1 regulates a Ras-dependent vascular smooth muscle proliferative injury response. Circulation , 2148-56 (2007)
Xu J, Rogers MB. Modulation of Bone Morphogenetic Protein (BMP) 2 gene expression by Sp1 transcription factors Gene , 221-9 (2007)
Ismat FA, Xu J, Lu MM, Epstein JA. The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice J Clin Invest , 2378-84 (2006)
Abrams KL, Xu J, Nativelle-Serpentini C, Dabirshahsahebi S, Rogers MB. An evolutionary and molecular analysis of Bmp2 expression J Biol Chem , 15916-28 (2004)
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Junwang Xu's activity on Nature Network
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