Lisa Munter's profile
What I do
I am working on the molecular mechanisms of Alzheimer’s disease. My focus is the generation of Aß peptides by two different secretases. Basically these studies are done in cell culture systems and with biochemical analyses. As especially the Aß peptide with 42 amino acids is the causative agent in Alzheimer’s disease, the modulation of the mechanism leading to Aß42 will directly influence the progress of the disease.
Affiliations
Lisa Munter has not yet stated an affiliation.
Location
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Interests
No interests have been listed by Lisa Munter.
Projects
Lisa Munter has not yet listed any projects.
Publications
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Kaden D, Munter L, Joshi M, Treiber C, Weise C, Bethge T, Voigt P, Schaefer M, Beyermann M, Reif B, Multhaup G. Homophilic Interactions of the Amyloid Precursor Protein (APP) Ectodomain Are Regulated by the Loop Region and Affect {beta}-Secretase Cleavage of APP. The Journal of biological chemistry (11) , 7271-9 (2008) (Epub 08 Jan 2008) PubMed ID:(18182389)
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Munter L, Voigt P, Harmeier A, Kaden D, Gottschalk K, Weise C, Pipkorn R, Schaefer M, Langosch D, Multhaup G. GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. The EMBO journal (6) , 1702-12 (2007) (Epub 01 Mar 2007) PubMed ID:(17332749 )