chris turck's profile
What I do
Affiliations
Current affiliations
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- Position
- Head, Proteomics and Biomarkers
- Company
- Max Planck Institute of Psychiatry
- Further information
Location
- City:
- None chosen
- Hub:
- None chosen
Interests
Research interests are concerned with the identification of biomarkers for affective and neurological disorders. Biomarkers will ultimately allow a more precise definition and categorization of mood disorders and in turn facilitate investigations of the pathogenesis of the diseases and enhance our ability for treatment.
Proteomic technologies promise to be of great value in molecular medicine, particularly in the detection and discovery of disease markers. The proteome is thought to be directly related to the phenotype of an organism and hence protein profiling will result in the most precise understanding of disease mechanisms as well as the molecular effects of drugs. Our biomarker detection efforts range from classical proteomics approaches such as quantitative mass spectrometry of brain tissue and body fluid proteins to phage display screens with cerebrospinal fluid antibodies.
Projects
see “What I do”
Publications
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ABRF-PRG2006 study: Relative protein qQuantitation. (Epub 18 May 2007) PubMed ID:(17513294)
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Arnott D, Gawinowicz M, Kowalak J, Lane W, Speicher K, Turck C, West K, Neubert T. ABRF-PRG04: differentiation of protein isoforms. Journal of biomolecular techniques : JBT (2) , 124-34 PubMed ID:(17496225)
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Brunner J, Bronisch T, Uhr M, Ising M, Binder E, Holsboer F, Turck C. Proteomic analysis of the CSF in unmedicated patients with major depressive disorder reveals alterations in suicide attempters. European archives of psychiatry and clinical neuroscience (6) , 438-40 PubMed ID:(16382377)
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Ditzen C, Jastorff A, Kessler M, Bunck M, Teplytska L, Erhardt A, Krömer S, Varadarajulu J, Targosz B, Sayan-Ayata E, Holsboer F, Landgraf R, Turck C. Protein biomarkers in a mouse model of extremes in trait anxiety. Molecular & cellular proteomics : MCP (10) , 1914-20 (Epub 14 Jun 2006) PubMed ID:(16775081)
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Krömer S, Kessler M, Milfay D, Birg I, Bunck M, Czibere L, Panhuysen M, Pütz B, Deussing J, Holsboer F, Landgraf R, Turck C. Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety. The Journal of neuroscience : the official journal of the Society for Neuroscience (17) , 4375-84 PubMed ID:(15858064)
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