• Philip Coan's profile

    • What I do

      Alterations in nutrient availability at critical developmental time windows during gestation may reprogram the conceptus leading to alterations in development and function of vital organs resulting in metabolic syndrome in adulthood.
      Therefore, I am researching how alterations in nutrient availability effect methylation, (imprinted) gene expression, structure and development of the mouse placenta and how they lead to fetal reprogramming in the womb

    • Affiliations

      Current

    • Interests

      Nutrition
      Fetal programming
      Neonatal physiology
      Metabolic Syndrome
      Genomic Imprinting
      Placenta development
      Insulin-like growth factor II

    • Projects

      Placental development and genomic imprinting in the mouse
      Nutritional programming of imprinted genes in the mouse placenta

    • Publications

      • Fowden, A.L., Forhead, A.J., Coan, P.M. and Burton, G.J.. The placenta and intrauterine programming. J. Neuroendocrinology 20 , 439-450 (2008)

      • Developmental dynamics of the definitive mouse placenta assessed by stereology. (Epub 18 Feb 2004) PubMed ID:(14973263)

      • Differential regulation of imprinting in the murine embryo and placenta by the Dlk1-Dio3 imprinting control region. (Epub 13 Dec 2006) PubMed ID:(17166925)

      • Genes and development--a workshop report. PubMed ID:(15033305 )

      • Imprinted genes in the placenta--a review. PubMed ID:(15837057)

      view all
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