Meredith Crosby's profile
What I do
From the basic research side, I am interested in understanding why aggressive cancers are able to survive under otherwise deleterious conditions, which include low oxygen (tumors). From this point, I am interesting in understanding how the E2F transcription factors contribute to tumor survival. I am interested in therapeutic resistance and how cancer cells adapt to new environments.
I am also involved in the World Academy of Young Scientists (WAYS), which serves as an internation voice for young scientists. Supported through UNESCO, it also has ties with the Young European Biotech Network (YEBN). In 2005, my paper focusing on science/business integrative approaches to sustainability and responsibility allows me to attend the World Science Forum in Budapest. In 2007, I served as a member of the Class of 2007 at the World Life Sciences Forum in Lyon.
Affiliations
Meredith Crosby has not yet stated an affiliation.
Location
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Interests
No interests have been listed by Meredith Crosby.
Projects
Hypoxia, DNA repair factors, and the tumor microenvironment.
Publications
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E2F4 Function in G(2): Maintaining G2-Arrest to Prevent Mitotic Entry with Damaged DNA. (10) (Epub 11 May 2007) PubMed ID:(17507799)
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Redox Regulation of Apoptosis before and after Cytochrome C Release. (1) , 1-9 PubMed ID:(16467897)
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Regulation of DNA repair in hypoxic cancer cells. PubMed ID:(17415527)
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Crosby M, Almasan A. Opposing roles of E2Fs in cell proliferation and death. Cancer biology & therapy (12) , 1208-11 (Epub 21 Dec 2004) PubMed ID:(15662116 )
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Crosby M, Jacobberger J, Gupta D, Macklis R, Almasan A. E2F4 regulates a stable G2 arrest response to genotoxic stress in prostate carcinoma. Oncogene (13) , 1897-909 (Epub 09 Oct 2006) PubMed ID:(17043659 )
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