Omid Akbari's profile
What I do
I am an Immunologist. The objective of my laboratory is to: characterize and define acquired and innate immune responses at mucosal surfaces; investigate the mechanisms underlying the regulation of those responses; explore the mechanisms by which those responses contribute to inflammatory, autoimmune allergic diseases and asthma; and determine means by which those responses can be specifically manipulated.
Affiliations
Current affiliations
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- Position
- Assistant Professor
- Company
- Harvard Medical School
- Further information
Location
- City:
- None chosen
- Hub:
- Boston
Interests
The studies and research interests of my laboratory can be categorized into four major areas:
-T cell subsets and immunoregulation of autoimmune diseases
-The role of dendritic cells and antigen presenting cells in regulation of immune responses
-The requirements for NKT cell activation, migration and homeostasis in the context of allergic disease and asthma
-Glycolipid antagonist therapies for allergic disease, asthma and other autoimmune diseases
Projects
Omid Akbari has not yet listed any projects.
Publications
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Akbari O. The role of iNKT cells in development of bronchial asthma: a translational approach from animal models to human. Allergy (8) , 962-8 (2006) PubMed ID:(16867051)
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Akbari O, Faul J, Hoyte E, Berry G, Wahlström J, Kronenberg M, DeKruyff R, Umetsu D. CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma. The New England journal of medicine (11) , 1117-29 (2006) PubMed ID:(16540612)
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Akbari O, Umetsu D. Role of regulatory dendritic cells in allergy and asthma. Current opinion in allergy and clinical immunology (6) , 533-8 (2004) PubMed ID:(15640695 )
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Stock P, Akbari O, Berry G, Freeman G, Dekruyff R, Umetsu D. Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nature immunology (11) , 1149-56 (2004) (Epub 26 Sep 2004) PubMed ID:(15448689)
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Akbari O, Stock P, Meyer E, Kronenberg M, Sidobre S, Nakayama T, Taniguchi M, Grusby M, DeKruyff R, Umetsu D. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nature medicine (5) , 582-8 (2003) (Epub 31 Mar 2003) PubMed ID:(12669034)