• Thomas Brody's profile

    • What I do

      My current effort in the laboratory is to identify enhancer elements involved in regulation of Drosophila neural precursor cell determinants.

    • Affiliations

      Current

    • Interests

      I am interested in gene regulation, specifically the structure of enhancers. I have collaborated in creating two programs to analyze enhancers, EvoPrinter and cis-Decoder. I have also built a cyberspace guide to Drosophila development, The Interactive Fly.

    • Projects

      Identification of Drosophila neural determinsnts that regulated temporally.
      Functional dissection of nerfin-1, deadpan and Pdm-1 enhancers.

    • Publications

      • Yavatkar A, Lin Y, Ross J, Fann Y, Brody T, Odenwald W. Rapid detection and curation of conserved DNA via enhanced-BLAT and EvoPrinterHD analysis. BMC genomics 9 , 106 (2008) (Epub 28 Feb 2008) PubMed ID:(18307801)

      • Brody T, Rasband W, Baler K, Kuzin A, Kundu M, Odenwald W. cis-Decoder discovers constellations of conserved DNA sequences shared among tissue-specific enhancers. Genome biology 8 (5) , R75 (2007) PubMed ID:(17490485)

      • Kuzin A, Kundu M, Brody T, Odenwald W. The Drosophila nerfin-1 mRNA requires multiple microRNAs to regulate its spatial and temporal translation dynamics in the developing nervous system. Developmental biology 310 (1) , 35-43 (2007) (Epub 24 Jul 2007) PubMed ID:(17714701 )

      • Kuzin A, Brody T, Moore A, Odenwald W. Nerfin-1 is required for early axon guidance decisions in the developing Drosophila CNS. Developmental biology 277 (2) , 347-65 (2005) PubMed ID:(15617679)

      • Odenwald W, Rasband W, Kuzin A, Brody T. EVOPRINTER, a multigenomic comparative tool for rapid identification of functionally important DNA. Proceedings of the National Academy of Sciences of the United States of America 102 (41) , 14700-5 (2005) (Epub 03 Oct 2005) PubMed ID:(16203978)

      view all
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