Joseph Antony's profile
What I do
I work with embryonic microglia, understanding the dynamics at the interface of hematopoietic and neuroectodermal stem cells mileu
Affiliations
Past affiliations
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- Position
- Post Doc
- Company
- Sickkids, Toronto, Canada
- Duration
- 2006 - Present
Location
- City:
- None chosen
- Hub:
- None chosen
Interests
My research interests lie in neurodevelopmental and neuropathological disorders. I am working to understand the role of microglia and how they influence brain development, thereby contributing to the pathogenesis of various pediatric neurological disorders. Towards this end, I am performing in vitro and in vivo assays using cortical stem cells to further understand how microglia modulate the timing of cell genesis. I would like to continue my research in understanding the role of genes modulating stem cell behavior in the brain, with the goal of manipulating stem cell mediated brain repair and regeneration.
Projects
Joseph Antony has not yet listed any projects.
Publications
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Antony J, Ellestad K, Hammond R, Imaizumi K, Mallet F, Warren K, Power C. The human endogenous retrovirus envelope glycoprotein, syncytin-1, regulates neuroinflammation and its receptor expression in multiple sclerosis: a role for endoplasmic reticulum chaperones in astrocytes. Journal of immunology (Baltimore, Md. : 1950) (2) , 1210-24 (2007) PubMed ID:(17617614)
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Antony J, van Marle G, Opii W, Butterfield D, Mallet F, Yong V, Wallace J, Deacon R, Warren K, Power C. Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination. Nature neuroscience (10) , 1088-95 (2004) (Epub 26 Sep 2004) PubMed ID:(15452578)
Contact
- email:
- josephmatthew [ at ] hotmail.com
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