Aaron Nelson's profile

What I do

I am currently a medical student at Tufts University School of Medicine. I expect to graduate in May 2009. I completed a PhD in Cell and Molecular Biology at the University of Pennsylvania, with a focus on host-pathogen interactions, innate immunity, inflammatory processes, and microbiology. I continued my studies as a post-doctoral fellow at the Karolinska Institute in Stockholm, Sweden, before returning to medical school.

Affiliations

Current

Location

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Interests

My interests revolve around technologic innovation in biomedicine. Specifically, I am interested in how the laboratory investigations are assembled into individual products which are then implemented in the clinic. I plan to pursue analysis and evaluation of products, technologies, companies and sectors to better understand trends in the translation of scientific knowledge into useful clinical applications.

My laboratory research background focused on the molecular means by which pathogenic and commensal bacteria interact with mammalian host species. My clinical training has been a broad approach to clinical analysis and problem-solving.

In my studies, I have worked both as an individual actor and as part of multidisciplinary teams. I have both supervised more junior scientists and students, and in turn been supervised and mentored by those with more experience than I. I have also had the opportunity to coordinate the activities of more senior colleagues to complete a specific project. I have developed the capacity to develop long-term plans with multiple contingencies, and to be flexible as unexpected data arise. In all endeavors, I have digested large volumes of technical literature rapidly, and written and published as frequently as possible.

Projects

I am currently working on a project through the Tufts University Center for the Study of Drug Development.

Publications

  • Nelson A, Ratner A, Barasch J, Weiser J. Interleukin-8 secretion in response to aferric enterobactin is potentiated by siderocalin. Infection and immunity 75 (6) , 3160-8 (2007) (Epub 09 Apr 2007) PubMed ID:(17420239)

  • Nelson A, Ries J, Bagnoli F, Dahlberg S, Fälker S, Rounioja S, Tschöp J, Morfeldt E, Ferlenghi I, Hilleringmann M, Holden D, Rappuoli R, Normark S, Barocchi M, Henriques-Normark B. RrgA is a pilus-associated adhesin in Streptococcus pneumoniae. Molecular microbiology 66 (2) , 329-40 (2007) (Epub 10 Sep 2007) PubMed ID:(17850254)

  • Nelson A, Roche A, Gould J, Chim K, Ratner A, Weiser J. Capsule enhances pneumococcal colonization by limiting mucus-mediated clearance. Infection and immunity 75 (1) , 83-90 (2007) (Epub 06 Nov 2006) PubMed ID:(17088346)

  • Nelson A, Barasch J, Bunte R, Weiser J. Bacterial colonization of nasal mucosa induces expression of siderocalin, an iron-sequestering component of innate immunity. Cellular microbiology 7 (10) , 1404-17 (2005) PubMed ID:(16153241)

  • Nelson A, Algon S, Munasinghe J, Graves O, Goumnerova L, Burstein D, Pomeroy S, Kim J. Magnetic resonance imaging of patched heterozygous and xenografted mouse brain tumors. Journal of neuro-oncology 62 (3) , 259-67 (2003) PubMed ID:(12777077)

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