Shekhar Mande's profile
What I do
Affiliations
Current affiliations
-
- Position
- Adjunct Professor of Biotechnology
- Company
- University of Hyderabad, Hyderabad
- Duration
- 2007 - Present
- Further information
-
- Position
- Staff Scientist
- Company
- Centre for DNA Fingerprinting and Diagnostics, Hyderaad
- Duration
- 2001 - Present
- Further information
Location
- City:
- None chosen
- Hub:
- None chosen
Interests
I am trained as a macromolecular crystallographer. I have been practicing structural biology (especially of M. tuberculosis proteins), experimental as well as computational for the last 15 years. Recently I have also developed interest in computational biology, especially in predicting large biomolecular networks.
Projects
Structural studies on M. tuberculosis toxin-antixon systems
Analysis of genome-wide protein:protein interactions
Publications
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Goyal K, Mande S. Exploiting 3D structural templates for detection of metal-binding sites in protein structures. Proteins (4) , 1206-18 (2008) PubMed ID:(17847089)
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Goyal K, Mohanty D, Mande S. PAR-3D: a server to predict protein active site residues. Nucleic acids research (Web Server issue) , W503-5 (2007) (Epub 03 May 2007) PubMed ID:(17478506)
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Yellaboina S, Goyal K, Mande S. Inferring genome-wide functional linkages in E. coli by combining improved genome context methods: comparison with high-throughput experimental data. Genome research (4) , 527-35 (2007) (Epub 05 Mar 2007) PubMed ID:(17339371)
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Goyal K, Qamra R, Mande S. Multiple gene duplication and rapid evolution in the groEL gene: functional implications. Journal of molecular evolution (6) , 781-7 (2006) (Epub 10 Nov 2006) PubMed ID:(17103057)
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Qamra R, Prakash P, Aruna B, Hasnain S, Mande S. The 2.15 A crystal structure of Mycobacterium tuberculosis chorismate mutase reveals an unexpected gene duplication and suggests a role in host-pathogen interactions. Biochemistry (23) , 6997-7005 (2006) PubMed ID:(16752890)
Contact
- email:
- shekhar [ at ] cdfd.org.in
Shekhar Mande's activity on Nature Network
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