• Jason Herschkowitz's profile

    • What I do

    • Affiliations

      Current

      Past

    • Interests

      My current interest is in breast cancer stem cells (aka tumor initiating cells) and their involvement in therapy resistance, recurrence, and metastasis. I also have a strong interest in how cancer stem cells and particularly the process of self-renewal may be regulated by epigenetic mechanisms.

    • Projects

      Jason Herschkowitz has not yet listed any projects.

    • Publications

      • Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1. Molecular cancer 7 (1) , 29 (2008) (Epub 07 Apr 2008) PubMed ID:(18394172 )

      • Bultman S, Herschkowitz J, Godfrey V, Gebuhr T, Yaniv M, Perou C, Magnuson T. Characterization of mammary tumors from Brg1 heterozygous mice. Oncogene 27 (4) , 460-8 (2008) (Epub 16 Jul 2007) PubMed ID:(17637742 )

      • Burkart M, Wren J, Herschkowitz J, Perou C, Garner H. Clustering microarray-derived gene lists through implicit literature relationships. Bioinformatics (Oxford, England) 23 (15) , 1995-2003 (2007) (Epub 30 May 2007) PubMed ID:(17537751 )

      • Herschkowitz J, Simin K, Weigman V, Mikaelian I, Usary J, Hu Z, Rasmussen K, Jones L, Assefnia S, Chandrasekharan S, Backlund M, Yin Y, Khramtsov A, Bastein R, Quackenbush J, Glazer R, Brown P, Green J, Kopelovich L, Furth P, Palazzo J, Olopade O, Bernard P, Churchill G, Van Dyke T, Perou C. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome biology 8 (5) , R76 (2007) PubMed ID:(17493263 )

      • Li Z, Tognon C, Godinho F, Yasaitis L, Hock H, Herschkowitz J, Lannon C, Cho E, Kim S, Bronson R, Perou C, Sorensen P, Orkin S. ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex. Cancer cell 12 (6) , 542-58 (2007) PubMed ID:(18068631 )

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