Tim Hubbard's profile
What I do
Worry about annotating vertebrate genomes, particularly human, through a mixture of automatic annotation through Ensembl and manual curation by Havana. Also involved in big sequencing projects, such as zebrafish genome.
Affiliations
Current affiliations
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- Position
- Head of Informatics
- Company
- Wellcome Trust Sanger Institute
- Duration
- 1997 - Present
- Further information
Past affiliations
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- Position
- Zeneca Fellow
- Company
- Centre for Protein Engineering, MRC Centre, Cambridge
- Duration
- 1990 - 1997
Location
- City:
- Cambridge, England, United Kingdom
- Hub:
- Cambridge
Interests
Long history in prediction and its evaluation, including involvement in CASP protein structure prediction competition. Still a predictor at heart, with research group using machine learning such as for motif discovery, see Tiffin. Interested in data sharing infrastructure (e.g. DAS). Member of advisory board of ukPMC so very interested in ways to exploit open access content.
Projects
Publications
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Integrating biological data - the Distributed Annotation System. BMC bioinformatics , S3 (2008) (Epub 22 Jul 2008) PubMed ID:(18673527)
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Andreeva A, Howorth D, Chandonia J, Brenner S, Hubbard T, Chothia C, Murzin A. Data growth and its impact on the SCOP database: new developments. Nucleic acids research (Database issue) , D419-25 (2008) (Epub 13 Nov 2007) PubMed ID:(18000004)
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Brosch M, Swamy S, Hubbard T, Choudhary J. Comparison of Mascot and X!Tandem performance for low and high accuracy mass spectrometry and the development of an adjusted Mascot threshold. Molecular & cellular proteomics : MCP (5) , 962-70 (2008) (Epub 23 Jan 2008) PubMed ID:(18216375)
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Cochrane G, Akhtar R, Aldebert P, Althorpe N, Baldwin A, Bates K, Bhattacharyya S, Bonfield J, Bower L, Browne P, Castro M, Cox T, Demiralp F, Eberhardt R, Faruque N, Hoad G, Jang M, Kulikova T, Labarga A, Leinonen R, Leonard S, Lin Q, Lopez R, Lorenc D, McWilliam H, Mukherjee G, Nardone F, Plaister S, Robinson S, Sobhany S, Vaughan R, Wu D, Zhu W, Apweiler R, Hubbard T, Birney E. Priorities for nucleotide trace, sequence and annotation data capture at the Ensembl Trace Archive and the EMBL Nucleotide Sequence Database. Nucleic acids research (Database issue) , D5-12 (2008) (Epub 26 Nov 2007) PubMed ID:(18039715)
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Doğruel M, Down T, Hubbard T. NestedMICA as an ab initio protein motif discovery tool. BMC bioinformatics , 19 (2008) (Epub 14 Jan 2008) PubMed ID:(18194537)
Network
Tim Hubbard's network is currently empty.
