What I do
I’m a structural biologist, mostly from the NMR side of the fence, but I also do some protein crystallography. I have a general interest in structural bioinformatics, “Web2.0” for science. The biological systems I currently study include the mitochondrial protein import machinary (TOM, TIM and SAM complexes), and the machinary involved in insertion and assembly of bacterial outer membrane proteins.
Affiliations
Current affiliations
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- Position
- Postdoctoral Researcher
- Company
- Department of Biochemisty and Molecular Biology (Bio21 Institute), University of Melbourne
- Further information
Location
- City:
- None chosen
- Hub:
- None chosen
Interests
Structural bioinformatics, protein structure by NMR and X-ray crytallography, protein transport and protein targeting, membrane protein folding and assembly, beta-barrel membrane proteins.
Projects
Structure and function of the mitochondrial protein protein import machinary and bacterial outer membrane protein insertion and assembly.
Publications
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Perry A, Rimmer K, Mertens H, Waller R, Mulhern T, Lithgow T, Gooley P. Structure, topology and function of the translocase of the outer membrane of mitochondria. Plant physiology and biochemistry : PPB / Société française de physiologie végétale (3) , 265-74 (2008) (Epub 03 Jan 2008) PubMed ID:(18272380)
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Gentle I, Perry A, Alcock F, Likic V, Dolezal P, Ng E, Purcell A, McConnville M, Naderer T, Chanez A, Charrière F, Aschinger C, Schneider A, Tokatlidis K, Lithgow T. Conserved Motifs Reveal Details of Ancestry and Structure in the Small TIM Chaperones of the Mitochondrial Intermembrane Space. Molecular biology and evolution (5) , 1149-60 (Epub 28 Feb 2007) PubMed ID:(17329230)
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Likić V, Perry A, Hulett J, Derby M, Traven A, Waller R, Keeling P, Koehler C, Curran S, Gooley P, Lithgow T. Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20. Journal of molecular biology (1) , 81-93 (Epub 28 Jan 2005) PubMed ID:(15733919)
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Perry A, Hulett J, Likić V, Lithgow T, Gooley P. Convergent evolution of receptors for protein import into mitochondria. Current biology : CB (3) , 221-9 PubMed ID:(16461275)
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Perry A, Hulett J, Lithgow T, Gooley P. 1H, 13C and 15N resonance assignments of the cytosolic domain of Tom20 from Arabidopsis thaliana. Journal of biomolecular NMR (3) , 198 PubMed ID:(16331427)
