David Decraene's profile

What I do

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Interests

ontology, semantic web

Projects

Publications

  • Decraene D, Smaers K, Maes D, Matsui M, Declercq L, Garmyn M. A low UVB dose, with the potential to trigger a protective p53-dependent gene program, increases the resilience of keratinocytes against future UVB insults. The Journal of investigative dermatology 125 (5) , 1026-31 (2005) PubMed ID:(16297205)

  • Decraene D, Smaers K, Gan D, Mammone T, Matsui M, Maes D, Declercq L, Garmyn M. A synthetic superoxide dismutase/catalase mimetic (EUK-134) inhibits membrane-damage-induced activation of mitogen-activated protein kinase pathways and reduces p53 accumulation in ultraviolet B-exposed primary human keratinocytes. The Journal of investigative dermatology 122 (2) , 484-91 (2004) PubMed ID:(15009734)

  • Decraene D, Van Laethem A, Agostinis P, De Peuter L, Degreef H, Bouillon R, Garmyn M. AKT status controls susceptibility of malignant keratinocytes to the early-activated and UVB-induced apoptotic pathway. The Journal of investigative dermatology 123 (1) , 207-12 (2004) PubMed ID:(15191562 )

  • Decraene D, Agostinis P, Bouillon R, Degreef H, Garmyn M. Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes. The Journal of biological chemistry 277 (36) , 32587-95 (2002) (Epub 17 Jun 2002) PubMed ID:(12070137)

  • Claerhout S, Decraene D, Van Laethem A, Van Kelst S, Agostinis P, Garmyn M. AKT delays the early-activated apoptotic pathway in UVB-irradiated keratinocytes via BAD translocation. The Journal of investigative dermatology 127 (2) , 429-38 (Epub 24 Aug 2006) PubMed ID:(16932738)


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