• The O.L.S. Buzz by Christie Wilcox

    A blog about anything and everything that piques the interest of a marine biologist, written for everyone else. Great for any Oompa Loompa of Science (O.L.S.) or the scientist in us all!

    • Here's one for you Brits. Though I don't think you're going to like it.

      Tuesday, 20 Jan 2009 - 17:33 UTC

      ResearchBlogging.orgI know a lot of people on here are from London/the UK in general. So perhaps you might want to know that a new study has further linked both estrogenic and anti-androgenic chemicals to declining male fertility in fish in UK rivers.

      When it comes to affecting male fertility, there are two major types of compounds that might have strong, negative impacts: estrogenics and anti-androgenics. Estrogenics, as the name implies, are pseudo-estrogens or estrogens, and tend to feminize males of a species. They are sought to derive from human sources like birth control pills. While they have not been shown to have as profound an effect on human males, they are generally considered responsible for most wildlife reproductive changes. In contrast, anti-androgenics, which change male reproduction by directly blocking testosterone, have been strongly linked to affects in humans, but have been less linked to natural outbreaks and effects. These include the less regulated bisphenols and phthalates (found in plastics, for example).

      This study, published in Environmental Health Perspectives, sought to look at both compound types and their effects on male fish in UK river systems. Because anti-androgens are less linked to wildlife problems, they are generally considered to be at low enough levels not to bother humans. Therefore, if anti-androgens were found to have profound effects on fish, it would mean that the river systems in the UK are chock full of emasculating compounds at levels which are probably high enough to worry people, too.

      And, of course, they did. Many areas had a hodgepodge of compounds, whose combined effects were synergistic. These effects included oocytes in the fish’ testes, increased levels of feminine hormones, and intersex fish. The combination of compounds far more accurately predicted feminization than each group alone, meaning that there are fewer differences between the reproductive disruption in fish and humans as previously thought.

      What this means for you British boys is that your water ain’t as safe as you might think. Of course, the UK is hardly unique in their levels of these compounds – they’re just the most recently tested. And some of these compounds, like those used in plastics, aren’t well regulated – though studies like this will hopefully start to change that. In the mean time, I suggest thinking a bit more carefully before microwaving food in plastic tubs and drinking any ’ole water…

      Susan Jobling, Robert W. Burn, Karen Thorpe, Richard Williams, Charles Tyler (2009). Statistical Modelling Suggests That Anti-Androgens in Wastewater Treatment Works Effluents are Contributing Causes of Widespread Sexual Disruption in Fish Living in English Rivers Environmental Health Perspectives DOI: 10.1289/ehp.0800197

      Last updated: Tuesday, 20 Jan 2009 - 17:33 UTC

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      • Comments

        • Date:
          Tuesday, 20 Jan 2009 - 20:13 UTC
          Åsa Karlström said:

          I do wonder though, seeing that testes are continously producing sperm during the life span, in contrast to the female eggs that are there from the get go, would it be possible to revoke the problem (inferility) if you give them increasing levels of testosterone?! Or is the damage done when you look at male fetuses in the womb?

          I think over all that the concern about what kind of water we all are drinking has been downplayed. It reminds me very much of the concern in the radioactivity lab… I needed to have geigers ON when I was in there since I didn’t see, smell or hear any danger unless they meters were buzzing… The same thing with water, as long as it is “clear” people tend to think it is “ok” right?!


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