Thomas Brody's profile
What I do
My current effort in the laboratory is to identify enhancer elements involved in regulation of Drosophila neural precursor cell determinants.
Affiliations
Current affiliations
-
- Position
- Staff Scientist
- Company
- National Institutes of Health
- Duration
- 1998 - Present
- Further information
-
- Position
- Staff Scientist
- Company
- Neural Cell-Fate Determinants section NINDS, NIH
- Duration
- 1998 - Present
- Further information
Location
- City:
- Washington, District of Columbia, United States
- Hub:
- Washington DC-Baltimore
Interests
I am interested in gene regulation, specifically the structure of enhancers. I have collaborated in creating two programs to analyze enhancers, EvoPrinter and cis-Decoder. I have also built a cyberspace guide to Drosophila development, The Interactive Fly.
Projects
Identification of Drosophila neural determinsnts that regulated temporally.
Functional dissection of nerfin-1, deadpan and Pdm-1 enhancers.
Publications
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Brody T, Rasband W, Baler K, Kuzin A, Kundu M, Odenwald W. Sequence conservation and combinatorial complexity of Drosophila neural precursor cell enhancers. BMC genomics , 371 (2008) (Epub 01 Aug 2008) PubMed ID:(18673565)
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Brody T, Yavatkar A, Lin Y, Ross J, Kuzin A, Kundu M, Fann Y, Odenwald W. Horizontal gene transfers link a human MRSA pathogen to contagious bovine mastitis bacteria. PLoS ONE (8) , e3074 (2008) (Epub 27 Aug 2008) PubMed ID:(18728754)
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Yavatkar A, Lin Y, Ross J, Fann Y, Brody T, Odenwald W. Rapid detection and curation of conserved DNA via enhanced-BLAT and EvoPrinterHD analysis. BMC genomics , 106 (2008) (Epub 28 Feb 2008) PubMed ID:(18307801)
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Brody T, Rasband W, Baler K, Kuzin A, Kundu M, Odenwald W. cis-Decoder discovers constellations of conserved DNA sequences shared among tissue-specific enhancers. Genome biology (5) , R75 (2007) PubMed ID:(17490485)
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Kuzin A, Kundu M, Brody T, Odenwald W. The Drosophila nerfin-1 mRNA requires multiple microRNAs to regulate its spatial and temporal translation dynamics in the developing nervous system. Developmental biology (1) , 35-43 (2007) (Epub 24 Jul 2007) PubMed ID:(17714701 )
Contact
- email:
- brodyt [ at ] mail.nih.gov
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