• New York Minutes by Sabbi Lall

    Science-related news, culture, characters and curiosities in New York.

    • Physics is so easy....

      Wednesday, 07 Oct 2009 - 02:39 UTC

      to explain this year with respect to Nobel Prizes, or apparently anyway. Was it me or did the news casters today breathe a sigh of relief as they discussed fiber optics, cell phones and cameras? So much easier than explaining DNA ends and the potential benefits understanding their maintenance and dysfunction might have. This seemed to generate many more ums, but maybe it was the sources I heard as the news first broke. I felt a little dispirited, telomeres being that amazing!

      Last updated: Wednesday, 07 Oct 2009 - 02:39 UTC

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      • Comments

        • Date:
          Wednesday, 07 Oct 2009 - 13:48 UTC
          Alejandro Correa said:

          Sabby – ¿Waiting another thing?. ¿Give me to an example, please?

        • Date:
          Wednesday, 07 Oct 2009 - 13:50 UTC
          Sabbi Lall said:

          I can’t, I’m so excited about the ribosome!

        • Date:
          Wednesday, 07 Oct 2009 - 14:43 UTC
          Richard Grant said:

          Me too!

        • Date:
          Wednesday, 07 Oct 2009 - 14:44 UTC
          Alyssa Gilbert said:

          Yay for physics being less confusing than everything else for once! Hehe!

        • Date:
          Wednesday, 07 Oct 2009 - 16:57 UTC
          Sabbi Lall said:

          I know, we have a double whammy with explaining telomeres and ribosomes now, whereas you can send people to their digital camera and retro-style fiber optic lamp. But still exciting!

        • Date:
          Wednesday, 07 Oct 2009 - 18:19 UTC
          Graham Steel said:

          +Short Musical Interlude+

          Talking of things, “so easy”, here’s a link to a wee ditty named So Easy (this is) I recorded/produced a few years ago. Dunno what “this” referred to in terms of the lyrics of the song, though. That said, I suspect it wasn’t OMNIGENOMICS !!

        • Date:
          Wednesday, 07 Oct 2009 - 19:09 UTC
          Alejandro Correa said:

          Is wonderfull the machinery of ribosomes!!

          And the clown fish in the blue water.

          Is the Nature, maybe!

        • Date:
          Wednesday, 07 Oct 2009 - 20:36 UTC
          Graham Steel said:

          @Alejandro / Chik Corea / Prof Correa, times may vary, global warming etc….

          I dunno, but here’s another clown fish:

          Right. Where were we, sorry.

        • Date:
          Wednesday, 07 Oct 2009 - 21:25 UTC
          Sabbi Lall said:

          Pretty cute, but lone clownfish make me sad since you know who was horrifically separated from his loving single parental situation.

        • Date:
          Wednesday, 07 Oct 2009 - 21:54 UTC
          Graham Steel said:

        • Date:
          Wednesday, 07 Oct 2009 - 22:36 UTC
          Stephen Curry said:

          So, if these chromosome end thingies are so amazing, could you tell a mere physicist how they work?

        • Date:
          Wednesday, 07 Oct 2009 - 22:49 UTC
          Sabbi Lall said:

          The 6 million dollar question! Part of the difficulty in explaining the end thingies is that the mechanisms for how they they work are complex and differ across organisms, and the reasons that you need special ends are complex to explain to start with (to a layperson not to a physicist of course). The rhibosome : ) on the other hand lends itself to cute analogies (I like the NY times- DNA is the “blueprint”, the ribosome “the factory floor” and we can “gum up” the bacterial version specifically using antibiotics). I’ll think some more for a good telomere analogy, there are some!

        • Date:
          Wednesday, 07 Oct 2009 - 23:21 UTC
          Eva Amsen said:

          The ribosome can be danced to be explained!

        • Date:
          Wednesday, 07 Oct 2009 - 23:56 UTC
          Alejandro Correa said:

          Right. Where were we, sorry

          In the machinery of ribosomes. See Eva up.

          ¡Very well composer and musican Chik Corea!

        • Date:
          Thursday, 08 Oct 2009 - 03:02 UTC
          Sabbi Lall said:

          I saw that video of translation for the first time relatively recently- that is crazy! Is there anyone out there who participated in it and how did they coordinate everyone? Thanks Eva!! It’d be cool to make a you tube on the making of that video.

          Alejandro Chick Corea it is and he is a brilliant composer but I also wanted to thank Graham for the Easy interlude!

        • Date:
          Thursday, 08 Oct 2009 - 17:54 UTC
          Lee Turnpenny said:

          Here’s a nice piece of trivia that might come in handy (in case you don’t know and ever get asked the question in a pub quiz): The ribosome is the most abundant object on the planet (err, that’s what it says somewhere in my first year biochemistry notes).

        • Date:
          Thursday, 08 Oct 2009 - 18:29 UTC
          Sabbi Lall said:

          By individuals, i.e. number of ribosomes per se? I wonder who calculated that and how? It could be right, thinking of organellar ribosomes too, but it doesn’t seem right. What counts as an object?

        • Date:
          Thursday, 08 Oct 2009 - 18:45 UTC
          Alejandro Correa said:

          The ribosome is the most abundant object on the planet

          And what is the importance?

          It’s like saying the most abundant of the world are ants. That means we have more formic acid production in the world.

          ¿We have more molecules of ATP?

        • Date:
          Thursday, 08 Oct 2009 - 19:39 UTC
          Sabbi Lall said:

          And how many feathers on all the chickens in the world? I guess it’s a wow factor question. Or one that a Bob Dylan song would ask.

        • Date:
          Thursday, 08 Oct 2009 - 19:43 UTC
          Graham Steel said:

          Nobel Prize Update

          @Eva, that was quite a find !!

          One is reliably informed that as an indirect result of the ramblings discussion on this thread:-

          A Nobel for Ribosome Structure

          Full details can be found on this blog post as of yesterday written by Derek Lowe on his blog, In The Pipeline

          About Derek Lowe – "Derek Lowe, an Arkansan by birth, got his BA from Jimi Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc

          “This was another Biology for Chemistry year for the Nobel Committee. Venkatraman Ramakrishnan (Cambridge), Thomas Steitz (Yale) and Ada Yonath (Weizmann Inst.) have won for X-ray crystallographic studies of the ribosome

        • Date:
          Thursday, 08 Oct 2009 - 19:53 UTC
          Alejandro Correa said:

          This answer my friend, depends as be interpret.

          No depend of the blowin’in the wind.

        • Date:
          Thursday, 08 Oct 2009 - 19:58 UTC
          Alejandro Correa said:

          Bob Dylan:

        • Date:
          Thursday, 08 Oct 2009 - 19:59 UTC
          Alejandro Correa said:

          Blowin’in the win

        • Date:
          Thursday, 08 Oct 2009 - 20:44 UTC
          Graham Steel said:

          Finally: a Nobel prize for the ribosome structure

          read on

        • Date:
          Thursday, 08 Oct 2009 - 20:55 UTC
          Graham Steel said:

          Prior to above, I spent 1.5 hours working on a para or two reply containing several links directly related to the starting point of the thread. Not for the 1st time, the NN platform let me down. Looked great in preview, but “submit” was a #fail despite checking all code aspects of my online comment.

          One is not amused.

        • Date:
          Thursday, 08 Oct 2009 - 21:05 UTC
          Stephen Curry said:

          @Graham – if you put more than 2 or 3 links in a comment, the spam-filters seem to block it automatically.

        • Date:
          Thursday, 08 Oct 2009 - 21:13 UTC
          Graham Steel said:

          @Stephen. Ah, that’s probably why. Thanks.

          If that’s the case, how very 1.0 NN – must do better.

        • Date:
          Thursday, 08 Oct 2009 - 23:25 UTC
          Alejandro Correa said:

          Graham – Prior to above, I spent 1.5 hours working on….

          In what blog?. Is a long time.

          I have had the same problem but Matt has filtered the access at the content of my commentary with link.

        • Date:
          Friday, 09 Oct 2009 - 00:02 UTC
          Alejandro Correa said:

          Sthepen – if you put more than 2 or 3 links in a comment, the spam-filters seem to block it automatically

          Thank you for the information.

        • Date:
          Friday, 09 Oct 2009 - 05:19 UTC
          Sabbi Lall said:

          Thanks for the link Graham- 1.5h is a long time (as Alejandro says), so I feel we lost out here (the lost opus of NN).

          At the link I can’t see the science background part (technology can be so frustrating when it’s so close to being enriching but so far!). But I can see the belly dancing ribosome (good video but it’s not belly dancing, it’s doing some kind of Saturday night fever thing?).

        • Date:
          Friday, 09 Oct 2009 - 06:11 UTC
          Richard Grant said:

          ‘Most abundant object’? We’re not thinking of RuBisCO, are we? Which is probably the most abundant protein on earth.

        • Date:
          Friday, 09 Oct 2009 - 08:42 UTC
          Matt Brown said:

          Graham – sorry about that. I was out yesterday and unable to overide the spam filters. I’ve ‘released’ your 1.5 hour masterpiece for all to see.

        • Date:
          Friday, 09 Oct 2009 - 12:43 UTC
          Graham Steel said:

          Thank you kindly, M@.

        • Date:
          Friday, 09 Oct 2009 - 12:50 UTC
          Alejandro Correa said:

          For the rest is very good work, I am watching, Graham.

        • Date:
          Friday, 09 Oct 2009 - 19:21 UTC
          Anna Vilborg said:

          According to Wikipedia “RuBisCO is also the most abundant protein in leaves, and it may be the most abundant protein on Earth”, but maybe if we keep cutting down trees we can help the ribosomes win the game?

        • Date:
          Friday, 09 Oct 2009 - 19:30 UTC
          Sabbi Lall said:

          We’re not thinking of RuBisCO, are we?

          lol- I know, Richard’s wheeling out the big gun. That said, chop down a tree, destroy thousands upon thousands of ribosomes (plastid specific ones too!). But yes, it would ultimately change the balance of macromolecular power! : )

        • Date:
          Saturday, 10 Oct 2009 - 10:31 UTC
          Lee Turnpenny said:

          I wasn’t talking about (protein) molecules; I said ‘… most abundant object… .’

          And what is the importance? Yer kidding, right?

        • Date:
          Saturday, 10 Oct 2009 - 13:58 UTC
          Alejandro Correa said:

          Lee – I wasn’t talking about (protein) molecules; I said most abundant object

          Object covering many things, it’s only for that reason.

          No is kidding, maybe I’ve don’t understanding.

        • Date:
          Saturday, 10 Oct 2009 - 23:39 UTC
          Sabbi Lall said:

          Hi Lee- you’ve started a discussion in my household about the abundance of nucleosomes (object or not) on the planet! A calculation was initiated, but quickly stalled.

        • Date:
          Friday, 16 Oct 2009 - 00:59 UTC
          Cath Ennis said:

          So, if these chromosome end thingies are so amazing, could you tell a mere physicist how they work?

          Dunno, but I explained telomeres to a carpenter once (my husband). The popular shoelaces / aglet analogy really does work very well! I was absolutely thrilled to hear him repeating it back (correctly) to his non-scientist friends a few months later.

        • Date:
          Saturday, 17 Oct 2009 - 00:48 UTC
          Sabbi Lall said:

          Nice job Cath! My other half is a teacher and an excellent explainer of things molecular biological so has a ton of analogies, but that is a good one!

          What does your husband build (that’s really cool)?

        • Date:
          Sunday, 18 Oct 2009 - 16:11 UTC
          Cath Ennis said:

          Well, when I first met him and asked him what he did, he said “I build spaceships!” He’s in the movie industry and is currently building an old WW2 bomber, but he has also made rocket ships, viking ships, fountains, giant globes, lots of neon signs, and the X-Jet, among other projects!

        • Date:
          Monday, 19 Oct 2009 - 00:43 UTC
          Sabbi Lall said:

          That is super cool!


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