Ludovic Bourre's profile

What I do

I work on peptide pro-drug development using peptide and photosensitiser used in photodynamic therapy, a promising modality of cancer diagnosis and treatment that utilises tumor specific accumulation of a photosensitiser, followed by irradiation with light at an appropriate wavelength inducing reactive oxygen species.

Affiliations

Current

Location

City:
London, England, United Kingdom
Hub:
London

Interests

Cancerology
Photodynamic therapy
Biochemistry
Microbiology
Peptide pro-drug

Projects

Ludovic Bourre has not yet listed any projects.

Publications

  • Bourré L, Giuntini F, Wilson M, Eggleston IM, MacRobert AJ. 5-aminolaevulinic acid peptide prodrugs enhance photosensitisation for photodynamic therapy Mol Cancer Ther. 7(6) , 1-10 (2008)

  • Dixon M, Bourré L, MacRobert A, Eggleston I. Novel prodrug approach to photodynamic therapy: Fmoc solid-phase synthesis of a cell permeable peptide incorporating 5-aminolaevulinic acid. Bioorganic & medicinal chemistry letters 17 (16) , 4518-22 (2007) (Epub 22 Jun 2007) PubMed ID:(17587577)

  • Bourré L, Simonneaux G, Ferrand Y, Thibaut S, Lajat Y, Patrice T. Synthesis, and in vitro and in vivo evaluation of a diphenylchlorin sensitizer for photodynamic therapy. Journal of photochemistry and photobiology. B, Biology 69 (3) , 179-92 (2003) PubMed ID:(12695032)

  • Bourré L, Thibaut S, Fimiani M, Ferrand Y, Simonneaux G, Patrice T. In vivo photosensitizing efficiency of a diphenylchlorin sensitizer: interest of a DMPC liposome formulation. Pharmacological research : the official journal of the Italian Pharmacological Society 47 (3) , 253-61 (2003) PubMed ID:(12591021)

  • Bourré L, Rousset N, Thibaut S, Eléouet S, Lajat Y, Patrice T. PDT effects of m-THPC and ALA, phototoxicity and apoptosis. Apoptosis : an international journal on programmed cell death 7 (3) , 221-30 (2002) PubMed ID:(11997666)

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