smitha karunakaran's profile
What I do
I am a PhD student at National Brain Research Centre, India.
Affiliations
Current affiliations
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- Position
- Doctoral student
- Company
- National Brain Research Centre
- Further information
Location
- City:
- None chosen
- Hub:
- None chosen
Interests
My research interests are oriented towards study of mechanisms involved in nervous system development and disease, specifically new therapies (regeneration studies) for Parkinson’s disease
Projects
My doctoral work focuses on deciphering the molecular mechanisms underlying the pathogenesis of sporadic Parkinson’s disease. I study the early signaling events involved as a trigger, which would be critical in determining the cell fate in terms of cell death vs survival.
Publications
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Karunakaran S, Saeed U, Ramakrishnan S, Koumar RC, Ravindranath V.. Constitutive expression and functional characterization of mitochondrial glutaredoxin (Grx2) in mouse and human brain. Brain Res. Sep 20; [Epub ahead of print] (2007 )
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Karunakaran S, Diwakar L, Saeed U, Agarwal V, Ramakrishnan S, Iyengar S, Ravindranath V.. Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid. FASEB J. 2007 Jul;21(9):2226-36
Contact
- email:
- smitha140 [ at ] rediffmail.com
smitha karunakaran's activity on Nature Network
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