Systems biology broadly involves the integrated mathematical treatment of biological phenomena. Such integrated systems biology and modelling ventures are increasingly being undertaken, by academics and practitioners alike, towards effective drug discovery and efficient treatment of diseases. This one-day seminar is intended both to stimulate research in this field and facilitate technology transfer and collaborations.

Programme

9:00 Registration & Refreshments

9:30 Welcome & Introduction – Dr Charles D. Immanuel (Imperial College London, UK)

Morning Session – Chair, Dr Charles D. Immanuel (Imperial College London, UK)

9:35 Systems Biology Initiatives in UK – Professor David Bogle (University College London, UK)

10:00 Systems Biology and New Opportunities for Medicine – Professor Francis J. Doyle, III (University of California, Santa Barbara, USA)

10:45 Engineering Self-Sustaining Systems: Differential Network-Based Drug Design – Professor Hans V. Westerhoff (Manchester Centre for Integrative Systems Biology, UK and Netherlands Institute for Systems Biology, Netherlands)

11:30 A Systems Approach to Disease From the Perspective of Computer-Aided Process Analysis – Professor Peter Wellstead (Hamilton Institute, NUI, Ireland)

12:15 Lunch

Afternoon Session – Chair, Professor Iqbal M. Mujtaba (University of Bradford, UK)

13:45 A Systems Engineering Approach to the Production of Biologics – Dr Sakis Mantalaris and Dr Cleo Kontoravdi (Imperial College London, UK)

14:30 Hybrid Modelling Strategies for Biological Systems – Dr Vivek Dua (University College London, UK)

15:15 Pharmaceutical and Biomedical Systems Engineering – An Integrated Approach for Drug Dosage Design – Dr Zoltan Nagy (Loughborough University, UK)

16:00 The Role of Pharmacokinetic/Pharmacodynamic Modelling in Drug Discovery – Dr Pinky Dua (GlaxoSmithKline, UK)

16:45 Questions & Discussion