• Boston blog by Boston

    All the Boston science news that's fit to blog. And then some. A group blog from Rob Pinsonneault and Corie Lok.

    • Darwinian Inspiration

      Sunday, 25 Jan 2009 - 04:00 UTC

      What better way to celebrate Charles Darwin’s 200th birthday, than with a symposium which highlights the vast diversity, brilliance, and accomplishments of today’s evolutionary biologists. This week, MIT hosted a three day symposium to celebrate the life and work of Charles Darwin, whose On the Origin of Species will turn 150 years old this year.

      Talk topics ranged from evolution on a molecular scale to paleontology, highlighting the breadth and implications of the evolutionary theory. I had the pleasure of sitting in on just a couple of the talks during the symposium, the first given by Pardis Sabeti on “Natural Selection in Humans and Pathogens.” Sabeti and her lab members designed software to crawl the human genome looking for “genomic signals of natural selection.” In general terms, the software looks for genes that are highly prevalent in the population but haven’t been there very long (relatively speaking), suggesting that they were selected for by evolutionary pressure. Using this approach, Sabeti identified a number of genes subjected to selective pressure, including a gene called LARGE, which can act as a mediator of Lassa virus entry into cells. Sabeti went on to set up a brand new lab in Nigeria, to track Lassa virus infection rates to identify genetic determinants of susceptibility to the virus. She is young, she is excited about her work, and she is making a large impact not only on evolutionary biology, but on world health.

      The following talk looked at evolution at a traditional, organismal level. Farish Jenkins has been mentioned around NN a number of times before. Not surprising, since his recent finding of Tiktaalik_, a missing link between shallow water fish and amphibious tetrapods shook the science (or "_Nature":http://www.nature.com/nature/journal/v440/n7085/abs/nature04639.html) world two years ago. Jenkins, in a highly animated, hugely entertaining and almost theatrical manner, described his many expeditions to the Canadian Arctic Archipelago, in the course of which he and his team discovered a fossil of a fish with a neck, elevated eyes on the same side of its head and wrists which could support the weight of its body. In other words, they found the missing link between animals who swam in the water and those that crawled out onto land to later (much later) become… human.


      Please pardon the fuzzy picture of Farish Jenkins. He rarely stood still for long – one of the many reasons his talk was so captivating.

      They were both thrilling talks. Yes, they were scientific seminars, but I walked away thrilled. Thrilled about how cool and engaging science can be, thrilled by the impact of the evolutionary theory and thrilled by the theory’s many interpretations.

      Happy Birthday, Mr. Darwin! Thank you for the Origin of Species and for inspiring a great symposium, which in turn inspired me. I guess that was the whole point, huh?

      Last updated: Sunday, 25 Jan 2009 - 04:00 UTC

      • Comments

        • Date:
          Sunday, 25 Jan 2009 - 16:16 UTC
          Stephen Curry said:

          “Great” post Anna. So, did you feel inspired to walk in their footsteps?

        • Date:
          Sunday, 25 Jan 2009 - 18:58 UTC
          Richard Wintle said:

          I love these kinds of things – just imagine discovering Tiktaalik; how exciting would that be?

          Are you by any chance intending to participate in this blog swarm? Your post, if judiciously re-dated (or nicely followed up with another one? please?) would be perfect.

        • Date:
          Monday, 26 Jan 2009 - 14:30 UTC
          Henry Gee said:

          I am privileged to say that I know Farish Jenkins. The two great things about him is that he wears his considerable erudition lightly; and he’s so much fun.

        • Date:
          Monday, 26 Jan 2009 - 16:29 UTC
          Anna Kushnir said:

          Stephen – Thanks, and absolutely not. Especially after reading your post. The monomaniacal obsession with science that many have told me is required for success is just not possible for me. Nor do I want it. Life is too short and there are too many things on this Earth to try. I am not going to devote myself to just the one, no matter how noble. I want to eat, and travel, and read, and frankly, sometimes I just want to sit on the couch and blog (if not nap). If that makes me a bad, or hopeless, scientist – so be it.

          Richard – I cannot even imagine discovering something like that. Honestly, I can’t even picture it, which made the talk just that much more captivating. Thanks so much for the link to the blog swarm. I will absolutely post something at that time, and will try to get some other NN folk to do the same!

          Henry – I thought you might know him! I am envious. I was close to name-dropping (your name) just to get a moment of his time, but thought better of it. I could imagine how fun it would be to go for a few pints with him, all his experiences and history. He is quite a showman. He really knows how to make science exciting and fun. He should be on TV. You should tell him :)

        • Date:
          Tuesday, 27 Jan 2009 - 17:53 UTC
          Richard Wintle said:

          Anna – further investigation (i.e., I actually read the guidelines) indicates that you could use an existing post rather than a new one, if you wanted to – just sign up and make sure to let them know which post you’re intending for them to aggregate.

          I, myself, will post not one but two… neither of which is written yet *ahem


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