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Blocking an mRNA localization element with a Morpholino

Jon Moulton

Friday, 22 May 2009 17:05 UTC

Binding a Morpholino across the Xenopus dead end localization element (a region of the dead end mRNA) prevents accumulation of dead end mRNA at the vegetal pole of the Xenopus oocyte:

Arthur PK, Clauβen M, Koch S, Tarbashevich K, Jahn O, Pieler T. Participation of Xenopus ELR-type proteins in vegetal mRNA localization during oogenesis. J Biol Chem. 2009 May 20. [Epub ahead of print]


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