This is a report of treatment of dystrophic dogs with Morpholino oligos.
Yokota T, Lu QL, Partridge T, Kobayashi M, Nakamura A, Takeda S, Hoffman E. Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs Annals of Neurology 2009 [epub ahead of print] doi 10.1002/ana.21627

Videos of treated and control dystrophic dogs:

Video 1, Non-treated Dystrophic Dog, 7 months old

Video 2, Non-treated Dystrophic Dog, 7 months old

Video 3, Treated Dystrophic Dog, 7 months old
After 5 x Weekly 120 mg/Kg Morpholino Oligo Cocktail Injections.

Video 4, Treated Dystrophic Dog, 4 months old
After 7 × 200 mg/Kg Morpholino Oligo Cocktail Injections.

Video 5, Treated Dystrophic Dog, 7 months old
After 11 × 120 mg/Kg Morpholino Oligo Cocktail Injections.

NIH press release on Morpholinos for Duchenne muscular dystrophy in a dog model of DMD:
http://www.nih.gov/news/health/mar2009/nichd-16.htm

Children’s National Medical Center press release:
http://www.childrensnational.org/pressroom/NewsReleases/FirstExonSkippingLargeAnimal.aspx