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KSRP binding to loop regions of miRNA: maturation regulation

Jon Moulton

Wednesday, 20 May 2009 19:06 UTC

Michele Trabucchi, Paola Briata, MariaFlor Garcia-Mayoral, Astrid D. Haase, Witold Filipowicz, Andres Ramos, Roberto Gherzi & Michael G. Rosenfeld. The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature advance online publication 20 May 2009

A protein that binds the loop region of an immature miRNA helps modulate the activity of Drosha and Dicer. This is a mechanism by which regulatory networks can affect maturation of miRNA.

Updated 21 May 2009 14:16 UTC


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