Regarding computing speed of linkage programs.
S.Rekha Reddy
Saturday, 07 July 2007 05:49 UTC
hi to all..
I m working on Human Genetics. I need to calculate LOD scores(using MLINK) for a family of around 50 individuals with 3 loops. It takes atleast 6-7 hrs to calculate for each marker.
1. Can anyone tell me how to increase the computing speed?
2. Can u suggest me good haplotyping programs for two point mapping?
Thanks in advance
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Replies
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Hi – I am not too sure about practical differences between LINKAGE and FASTLINK, maybe the fastlink documentation can help?
Barbara
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How can i calculate the maximum lod score can be obtained from a large family?
1.) 13/15 affecteds
2.) Few Afftds not sharing
Will the penetrance affects the lod score?thanks in advance
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