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Profile
Welcome to the CFG subgroup dedicated to Glycans in immune cell communication.
Topics of interest include:
1. Glycan-mediated trafficking of leukocytes
2. Regulation of cell signaling receptors
3. Regulation of cell fate during differentiation
4. Glycan-binding proteins: Selectins (C-type lectins), Siglecs, GalectinsYour Subgroup Leader is Dr. Paul Crocker, of the University of Dundee (UK).
Please join the conversation!
- Website:
- Group website
- Admin contact:
- Heather Buschman and Paul Crocker
- Tags:
- cell communication cell signaling glycomics glycobiology glycans biochemistry microbiology immunology protein microarray carbohydrate sugar leukocytes selectins siglecs galectins life-science health-medicine interdisciplinary-research
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Discussion
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Reagents available ( 5 replies )
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Discussion topics for our first meeting in November? ( 2 replies )
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Members'
publications-
Albert H, Collin M, Dudziak D, Ravetch J, Nimmerjahn F. In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner. Proceedings of the National Academy of Sciences of the United States of America (39) , 15005-9 (2008) (Epub 24 Sep 2008) PubMed ID:(18815375)
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Kawashima H, Petryniak B, Hiraoka N, Mitoma J, Huckaby V, Nakayama J, Uchimura K, Kadomatsu K, Muramatsu T, Lowe J, Fukuda M. N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules. Nature immunology (11) , 1096-104 (2005) (Epub 09 Oct 2005) PubMed ID:(16227985)
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Mitoma J, Bao X, Petryanik B, Schaerli P, Gauguet J, Yu S, Kawashima H, Saito H, Ohtsubo K, Marth J, Khoo K, von Andrian U, Lowe J, Fukuda M. Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment. Nature immunology (4) , 409-18 (2007) (Epub 04 Mar 2007) PubMed ID:(17334369 )
Group members can post their publications here from their profile page.
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