Hi, In past number of methods have been developed for predicting subcellular location of a protein. Recently, we also developed a subcellular method ESLpred2 . In general new methods are technically sound and more accurate than previous methods. Publishing a paper is one issue and its application in real-life is another issue. Publishing any technically sound paper is not very difficult in any bioinformatics journal. The question is whether it is worth to publish too many papers on subcellular localization.

I wants to know from group members particularly biologist whether they are using these methods for their research work or not. I always feel that bioinformatician should develop method useful for experimentalists not simply technically better methods. I will highly appreciate if you please send your comments whether these methods have any use for biologist or any experimental scientists.