Transplanted primordial germ cells produced viable gametes (and offspring!)
Jon Moulton
Tuesday, 02 October 2007 00:06 UTC
Primordial germ cells (PGC) were transplanted across species, even across genera, into zebrafish with host PGC inactivated by Dead End Morpholinos. Offspring were produced after natural spawning from gametes made by daughter cells of the transplanted PGC.
Saito T, Goto-Kazeto R, Arai K, Yamaha E.
Xenogenesis in Teleost Fish Through Generation of Germ-Line Chimeras by Single Primordial Germ Cell Transplantation.
Biol Reprod. 2007 Sep 26; [Epub ahead of print]
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