PhD Students forum: topic
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Cell Cycle GRNs for Childhood Leukemia
Amphun Chaiboonchoe
Monday, 01 October 2007 02:00 UTC
I currently doing my PhD about “Reverse engineering of gene regulatory networks (GRNs) in Childhood leukaemia based on microarray data
and Neural Networks”
I review so many article and have question about
1. Do the cell cycle are the same for every tissues?
2. There are many databases of cell cycle genes but the total cell cycle numbers are different,why and what is the best to use for reference?
3. I try to find GRNs or pathway of Acute lymphoblastic leukemia in general but I can not find any.Is anyone have idea about this?
Thank you for any suggestion or comments.
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Replies
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Don’t know much about cell cycle..
but a very good example of differential cell cycle is female overy.. where a cell cycle arrest in prophase is found in all in germ cells but not in males. guess wot.. a role of p63 is coming out..
If you know about Frank’s work in Harvard .. u’ll know more in detail..
here is a link..
http://cellbio.med.harvard.edu/faculty/mckeon/
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